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CAS 28036-31-9

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2-Methylimidazo[1,2-a]pyridin-3-amine

Description:
2-Methylimidazo[1,2-a]pyridin-3-amine is a heterocyclic aromatic amine characterized by its fused imidazole and pyridine rings, with a methyl group at the second position of the imidazole ring and an amino group at the third position of the pyridine ring. This compound is of interest due to its potential role as a mutagen and carcinogen, often studied in the context of food safety and toxicology, particularly in cooked meats where it can form during the cooking process. It is a pale yellow to brown solid that is soluble in organic solvents but has limited solubility in water. The compound's structure contributes to its reactivity, particularly in biological systems, where it can undergo metabolic activation to form DNA adducts. Its presence in various environmental and biological matrices raises concerns regarding human exposure and health risks, prompting ongoing research into its mechanisms of action and potential regulatory measures. Safety data sheets should be consulted for handling and exposure guidelines due to its toxicological properties.
Formula:C8H9N3
InChI:InChI=1S/C8H9N3/c1-6-8(9)11-5-3-2-4-7(11)10-6/h2-5H,9H2,1H3
InChI key:InChIKey=KTIGGQXUSNNTRK-UHFFFAOYSA-N
SMILES:NC=1N2C(=NC1C)C=CC=C2
Synonyms:
  • 2-Methylimidazo[1,2-a]pyridin-3-amine
  • 3-Amino-2-methylimidazo[1,2-a]pyridine
  • Imidazo[1,2-a]pyridine, 3-amino-2-methyl-
  • Imidazo[1,2-a]pyridine,3-amino-2-methyl- (8CI)
  • Imidazo[1,2-a]pyridin-3-amine, 2-methyl-
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