CAS 28045-02-5

Monamycin D1 (8CI,9CI)

Description:

Monamycin D1, with the CAS number 28045-02-5, is a naturally occurring antibiotic that belongs to the class of compounds known as aminoglycosides. It is produced by certain strains of Streptomyces bacteria. This compound exhibits a complex molecular structure characterized by multiple functional groups, which contribute to its biological activity. Monamycin D1 is known for its ability to inhibit bacterial protein synthesis, making it effective against a range of Gram-positive and some Gram-negative bacteria. Its mechanism of action involves binding to the bacterial ribosome, disrupting the translation process. Additionally, Monamycin D1 has been studied for its potential applications in treating infections, although its clinical use may be limited due to resistance issues and toxicity concerns associated with aminoglycosides. The compound's stability, solubility, and pharmacokinetic properties are important factors that influence its efficacy and safety profile in therapeutic contexts. Overall, Monamycin D1 represents a significant area of interest in antibiotic research and development.

Formula: C₃₄H₅₇N₇O₈

Synonyms:

• N-[1-[N-[[2-[[D-Hexahydro-2-(L-erythro-2-hydroxy-3-methyl-1-oxopentyl)-3-pyridazinyl]carbonyl]-L-hexahydro-cis-5-hydroxy-3-pyridazinyl]carbonyl]-N-methyl-D-leucyl]-trans-4-methyl-L-prolyl]-D-valinep-lactone
• D-Valine, N-[1-[N-[[2-[[D-hexahydro-2-(L-erythro-2-hydroxy-3-methyl-1-oxopentyl)-3-pyridazinyl]carbonyl]-L-hexahydro-cis-5-hydroxy-3-pyridazinyl]carbonyl]-N-methyl-D-leucyl]-trans-4-methyl-L-prolyl]-,p-lactone
• 2H-Dipyridazino[1,6-d:1',6'-g]pyrrolo[1,2-m][1,4,7,10,13,16]oxapentaazacyclooctadecine,cyclic peptide deriv.

Monamycin D1

CAS: 28045-02-5

Monamycin D1 is a lipopeptide antibiotic with activity against Gram-positive bacteria.

Formula: C₃₄H₅₇N₇O₈

Molecular weight: 691.86

Ref: TM-TN10762