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CAS 28053-08-9

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Uridine 5′-(trihydrogen diphosphate), P′-α-D-glucopyranosyl ester, sodium salt (1:2)

Description:
Uridine 5′-(trihydrogen diphosphate), P′-α-D-glucopyranosyl ester, sodium salt (1:2), commonly referred to as UDP-glucose, is a nucleotide sugar involved in various biochemical processes, particularly in glycogen synthesis and carbohydrate metabolism. This compound features a uridine base linked to a diphosphate group and a glucose moiety, making it a key player in the transfer of glucose units during glycosylation reactions. UDP-glucose is typically found as a sodium salt, which enhances its solubility in aqueous solutions. It is characterized by its role as a substrate for glycosyltransferases, enzymes that catalyze the transfer of sugar moieties to acceptor molecules. The presence of multiple phosphate groups contributes to its high-energy characteristics, facilitating the transfer of glucose. UDP-glucose is also involved in the biosynthesis of polysaccharides and plays a crucial role in cellular signaling pathways. Its stability and reactivity make it an important molecule in metabolic pathways, particularly in the synthesis of glycogen and glycoproteins.
Formula:C15H24N2O17P2·2Na
InChI:InChI=1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;/m1../s1
InChI key:InChIKey=ZIEBASYWDSMHND-QBNUFUENSA-N
SMILES:O[C@H]1[C@@H](O[C@H](COP(OP(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)(=O)O)(=O)O)[C@H]1O)N3C(=O)NC(=O)C=C3.[Na]
Synonyms:
  • Disodium UDP-glucose
  • Disodium uridine diphosphoglucose
  • P1-uridine-5 P2-glucose-1 disodium pyrophosphate
  • UDP-a-D-Glucose, Disodium Salt
  • Udp-G
  • Uridine 5'-Diphosphoglucose Disodium
  • Uridine 5-diphosphoglucose disodium salt
  • Uridine 5′-(trihydrogen diphosphate), P′-α-<span class="text-smallcaps">D</span>-glucopyranosyl ester, disodium salt
  • Uridine 5′-(trihydrogen diphosphate), P′-α-<span class="text-smallcaps">D</span>-glucopyranosyl ester, sodium salt (1:2)
  • Uridine 5′-(trihydrogen pyrophosphate), mono-α-<span class="text-smallcaps">D</span>-glucopyranosyl ester, disodium salt
  • See more synonyms
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