CAS 280744-09-4

3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

Description:

3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione, with the CAS number 280744-09-4, is a synthetic organic compound characterized by its complex molecular structure, which includes a pyrrole ring and multiple aromatic substituents. This compound typically exhibits properties associated with heterocyclic compounds, such as potential biological activity due to its ability to interact with various biological targets. The presence of the dichlorophenyl group may enhance its lipophilicity and influence its pharmacokinetic properties. Additionally, the indole moiety is known for its role in various biological processes, potentially contributing to the compound's activity. The compound may also display unique optical properties due to its conjugated system, which can affect its reactivity and stability. Overall, this substance is of interest in medicinal chemistry and may be explored for its potential therapeutic applications, particularly in the development of novel pharmaceuticals. However, specific characteristics such as solubility, melting point, and reactivity would require empirical data for precise evaluation.

Formula: C₁₉H₁₂Cl₂N₂O₂

InChI: InChI=1S/C19H12Cl2N2O2/c1-23-9-13(11-4-2-3-5-15(11)23)17-16(18(24)22-19(17)25)12-7-6-10(20)8-14(12)21/h2-9H,1H3,(H,22,24,25)

InChI key: InChIKey=JCSGFHVFHSKIJH-UHFFFAOYSA-N

SMILES: O=C1C(C=2C=3C(N(C)C2)=CC=CC3)=C(C(=O)N1)C4=C(Cl)C=C(Cl)C=C4

Synonyms:

• 1H-Pyrrole-2,5-dione, 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-
• Sb 216763
• Sb216763
• 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
• 3-(2,4-Dichlorophenyl)-4-...
• 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

SB 216763

CAS: 280744-09-4

Formula: C₁₉H₁₂Cl₂N₂O₂

Purity: >98.0%(HPLC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 371.22

Ref: 3B-B5716

SB216763

CAS: 280744-09-4

Formula: C₁₉H₁₂Cl₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 371.2168

Ref: IN-DA00BCKO

SB 216763

CAS: 280744-09-4

SB 216763

Purity: ≥98%

Molecular weight: 371.22g/mol

Ref: 54-BUP09960

3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

CAS: 280744-09-4

3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

Purity: 98%

Molecular weight: 371.21678g/mol

Ref: 54-OR1021332

SB 216763

CAS: 280744-09-4

Formula: C₁₉H₁₂N₂O₂Cl₂

Purity: ≥ 98.0%

Color and Shape: Orange, pink or red solid or powder

Molecular weight: 371.22

Ref: 7W-GL9739

SB 216763

CAS: 280744-09-4

SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).

Formula: C₁₉H₁₂Cl₂N₂O₂

Purity: 98.9% - 99.13%

Color and Shape: Solid

Molecular weight: 371.22

Ref: TM-T3077

SB 216763

CAS: 280744-09-4

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 371.2200012207031

Ref: 10-F047263

SB 216763

Controlled Product

CAS: 280744-09-4

Applications SB 216763 is a potent and selective cell permeale ATP-competitive inhibitor of GSK3a. It stimulates glycogen synthesis in Chang human liver cells.
References Li, L. et al.: ACS Med. Chem. Lett., 6, 548 (2015);

Formula: C₁₉H₁₂Cl₂N₂O₂

Color and Shape: Neat

Molecular weight: 371.22

Ref: TR-S154605

SB 216763

CAS: 280744-09-4

GSK3 serine/threonine protein kinase inhibitor; neuroprotective;cardioprotective

Formula: C₁₉H₁₂Cl₂N₂O₂

Purity: Min. 95%

Molecular weight: 371.22 g/mol

Ref: 3D-FD75068