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CAS 280783-56-4

:

8-[(1S,3aS)-2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one

Description:
The chemical substance known as 8-[(1S,3aS)-2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, with the CAS number 280783-56-4, is a complex organic compound characterized by its unique spirocyclic structure, which incorporates both nitrogen and carbon atoms. The presence of multiple nitrogen atoms in its triaza framework suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. The hexahydro-phenalenyl moiety contributes to its hydrophobic characteristics, which may influence its solubility and biological activity. Additionally, the compound's stereochemistry, indicated by the (1S,3aS) configuration, may play a crucial role in its interaction with biological targets, affecting its efficacy and safety profile. Overall, this compound exemplifies the intricate design often found in drug-like molecules, combining structural complexity with potential therapeutic applications. Further studies would be necessary to elucidate its specific properties, including its reactivity, stability, and biological effects.
Formula:C26H31N3O
InChI:InChI=1S/C26H31N3O/c30-25-26(29(18-27-25)21-9-2-1-3-10-21)14-16-28(17-15-26)23-13-12-20-7-4-6-19-8-5-11-22(23)24(19)20/h1-3,5,8-11,20,23H,4,6-7,12-18H2,(H,27,30)/t20-,23-/m0/s1
InChI key:InChIKey=JLFMYEAXZNPWBK-REWPJTCUSA-N
SMILES:O=C1C2(N(CN1)C3=CC=CC=C3)CCN(CC2)[C@@H]4C=5C=6[C@](CC4)(CCCC6C=CC5)[H]
Synonyms:
  • 8-[(1S,3aS)-2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
  • 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(1S,3aS)-2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl]-1-phenyl-
  • Ro 64-6198
  • Ro 64-6198 >=98% (HPLC)
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Found 2 products.
  • Ro 64-6198
    Targetmol
    + Info

    Ro 64-6198

    CAS:
    Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.
    Formula:C26H31N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:401.54

    Ref: TM-T16772

  • Ro 64-6198
    Biosynth
    + Info

    Ro 64-6198

    CAS:
    <p>Ro 64-6198 is a specific agonist for orphanin receptors. It has been shown to have antinociceptive and cholinergic effects in animal experiments, as well as to increase brain activity. Ro 64-6198 activates the orphanin receptor and has been shown to be effective in a pain model. This drug binds to the orphanin receptor and increases its binding affinity by 10-fold, which is sufficient to activate the receptor. The effective dose of Ro 64-6198 has not yet been determined, but it is likely that it will be less than 1 mg/kg.</p>
    Formula:C26H31N3O
    Purity:Min. 95%
    Molecular weight:401.54 g/mol

    Ref: 3D-FLA78356

    25mg
    1,124.00€
    50mg
    1,563.00€