CAS 2809-21-4

(1-Hydroxyethylidene)-1,1-diphosphonic acid

Description:

(1-Hydroxyethylidene)-1,1-diphosphonic acid, commonly referred to as HEDP, is a phosphonic acid derivative characterized by its ability to chelate metal ions, making it useful in various applications, particularly in water treatment and industrial processes. It features two phosphonic acid groups and a hydroxyethylidene moiety, which contribute to its strong affinity for calcium and other divalent metal ions. HEDP is typically a colorless to pale yellow liquid or solid, soluble in water, and exhibits excellent stability under a range of pH conditions. Its chelating properties help prevent scale formation and corrosion in water systems, making it valuable in cooling water systems, oilfield applications, and detergents. Additionally, HEDP is known for its low toxicity and environmental compatibility, which enhances its appeal in various formulations. The compound is also utilized in the agricultural sector as a fertilizer additive to improve nutrient availability. Overall, HEDP is a versatile chemical with significant industrial relevance due to its unique chemical structure and properties.

Formula: C₂H₈O₇P₂

InChI: InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9)

InChI key: InChIKey=DBVJJBKOTRCVKF-UHFFFAOYSA-N

SMILES: C(P(=O)(O)O)(P(=O)(O)O)(C)O

Synonyms:

• (1-Hydroxyaethyliden)-Diphosphonsaeure
• (1-Hydroxyethane-1,1-Diyl)Bis(Phosphonate)
• 1-Hydroxy-1,1-diphosphonoethane
• 1000Sl
• Ehdp
• Ethidronate
• Ethydronate
• Etidronate
• Etidronisaure
• Hdepa
• Hedp
• Hedpa
• Ksidifon
• Oedf
• Oedfk
• Oedp
• Wayplex
• Xidifon
• Xidiphone
• Xydiphone
• 1-Hydroxyethane-1,1-diphosphonic Acid
• Phosphonic acid, (1-hydroxyethylidene)di-
• 1-Hydroxyethylidene diphosphonic Acid
• Hydroxyethylidenedi(phosphonic acid)
• disodium (1-hydroxyethane-1,1-diyl)bis[hydrogen(phosphonate)]
• 1-HYDROXYETHYLIDENEDI(PHOSPHONIC ACID)
• Phosphonic acid, (1-hydroxyethylidene)bis-
• Hydroxyethylidine Diphosphonic Acid
• Phosphonic acid, P,P′-(1-hydroxyethylidene)bis-
• Etidronic acid
• 1-hydroxy ethylene-1,1-diphosphonic acid
• 1-Hydroxyethane-1,1-diphosphonic acid
• 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid
• Hydroxy Ethylidene-1,1-Diphosphonic Acid
• HydroxyEthylidene Diphosphonic acid

1-Hydroxyethane-1,1-diphosphonic Acid (ca. 60% in Water, ca. 4.2mol/L)

CAS: 2809-21-4

Formula: C₂H₈O₇P₂

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 206.03

Ref: 3B-H0587

1-Hydroxyethylidene-1,1-diphosphonic acid, min. 95% HEDP

CAS: 2809-21-4

1-Hydroxyethylidene-1,1-diphosphonic acid, min. 95% HEDP

Formula: C(OH)(CH₃)(PO₃H₂)₂

Purity: min. 95%

Color and Shape: white pwdr.

Molecular weight: 206.03

Ref: 08-15-2900

1-Hydroxyethylene-(1,1-diphosphonic acid)

CAS: 2809-21-4

1-Hydroxyethylene-(1,1-diphosphonic acid)

Purity: 60% in water

Molecular weight: 206.03g/mol

Ref: 54-OR98031

Etidronic acid

CAS: 2809-21-4

Etidronic acid

Purity: ≥95%

Molecular weight: 206.03g/mol

Ref: 54-BUP18216

Etidronic acid

CAS: 2809-21-4

Formula: C₂H₈O₇P₂·xH₂O

Purity: ≥ 90.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 206.03 (anhydrous)

Ref: 7W-GK9134

(1-Hydroxyethane-1,1-diyl)diphosphonic acid (ca. 60% in Water, ca. 4.2mol/L)

CAS: 2809-21-4

Purity: 98.0%

Color and Shape: Liquid, No data available.

Molecular weight: 206.02699279785156

Ref: 10-F210597

Etidronic acid

CAS: 2809-21-4

Etidronic acid (HEDP) is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.

Formula: C₂H₈O₇P₂

Purity: 99.93% - ≥95%

Color and Shape: Liquid Syrup

Molecular weight: 206.03

Ref: TM-T0308

Etidronate

Controlled Product

CAS: 2809-21-4

Stability Very Hygroscopic
Applications Etidronate is used as a calcium regulator. Etidronic acid is a bisphosphonate antiresorptive agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Francis, M.D., et al.: Science, 165, 1264 (1969), Jowsey, J., et al.: J. Lab. Clin. Med. , 76, 126 (1970), Altman, R.D.: N. Engl. J. Med., 79, 583 (1985)

Formula: C₂H₈O₇P₂

Color and Shape: Neat

Molecular weight: 206.028

Ref: TR-E934995

1-Hydroxyethylidene-1,1-diphosphonic acid - 60% aqueous solution,~4.2mol/L

CAS: 2809-21-4

1-Hydroxyethylidene-1,1-diphosphonic acid (HEDP) is a phosphonate that has been used as an inhibitor of the enzyme histone deacetylase. HEDP inhibits collagen production and root formation in cells. It also inhibits the uptake and mineralization of calcium by skin cells. HEDP has a strong inhibitory effect on protein synthesis, which may be due to its ability to bind to the active site of the enzyme protein kinase. In a short-term exposure experiment using an experimental model, HEDP caused significant cellular damage in the skin, which included increased cell death and decreased cell proliferation. HEDP also caused severe disruption of collagen fibers in the dermis layer of the skin.

Formula: C₂H₈O₇P₂

Purity: (Titration) 59.0 To 65.0%

Color and Shape: White Clear Liquid

Molecular weight: 206.03 g/mol

Ref: 3D-FH15419