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CAS 2809982-20-3

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  • EGFR-IN-132
    Targetmol
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    EGFR-IN-132

    CAS:
    <p>EGFR-IN-132 (Compound 23) is an EGFR inhibitor effective against various EGFR mutations including the wild-type, L858R/T790M, d19/T790M, L858R/T790M/C797S, and d19/T790M/C797S with IC50 values of 1.6, 0.025, 0.019, 0.022, and 0.029 nM, respectively. This compound demonstrates favorable pharmacokinetics with high oral bioavailability.</p>
    Formula:C27H31N7O3
    Color and Shape:Solid
    Molecular weight:501.58

    Ref: TM-T201638