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CAS 2810137-86-9

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  • XOR/URAT1-IN-1

    CAS:
    Compound II15, known as XOR/URAT1-IN-1, serves as a dual inhibitor targeting xanthine oxidoreductase (XOR) and uric acid transporter 1 (URAT1), exhibiting IC50 values of 6 nM and 12.9 μM, respectively. This compound effectively reduces uric acid levels in a mouse model of acute hyperuricemia induced by potassium oxonate and hypoxanthine.
    Formula:C18H13ClN2O3
    Molecular weight:340.76