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CAS 2810809-10-8

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  • SIK2-IN-3
    Targetmol
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    SIK2-IN-3

    CAS:
    <p>SIK2-IN-3 is an orally active selective inhibitor of SIK1/2 with IC50 values of 0.128/0.084 μM. It hinders the phosphorylation of CRTC3 and suppresses the production of pro-inflammatory factors in myeloid cells. Additionally, SIK2-IN-3 alleviates systemic and tissue inflammatory responses in a mouse anti-CD40 colitis model.</p>
    Formula:C23H24N6O2
    Color and Shape:Solid
    Molecular weight:416.48

    Ref: TM-T207716