CAS 28116-23-6

p-Hydroxyphenylacetylglycine

Description:

p-Hydroxyphenylacetylglycine, with the CAS number 28116-23-6, is an organic compound characterized by its structure, which includes a phenolic hydroxyl group, an acetyl group, and a glycine moiety. This compound is typically classified as an amino acid derivative and is known for its potential applications in pharmaceuticals and biochemistry. It exhibits properties such as solubility in polar solvents, which is common for compounds containing hydroxyl groups. The presence of the p-hydroxyphenyl group contributes to its potential antioxidant activity, while the acetyl and glycine components may influence its biological interactions and metabolic pathways. p-Hydroxyphenylacetylglycine may also be studied for its role in various biochemical processes, including its potential effects on enzyme activity and its interactions with other biomolecules. Overall, this compound represents a unique combination of functional groups that may confer specific biological activities, making it of interest in medicinal chemistry and related fields.

Formula: C₁₀H₁₁NO₄

InChI: InChI=1S/C10H11NO4/c12-8-3-1-7(2-4-8)5-9(13)11-6-10(14)15/h1-4,12H,5-6H2,(H,11,13)(H,14,15)

InChI key: InChIKey=CPPDWYIPKSSNNM-UHFFFAOYSA-N

SMILES: C(C(NCC(O)=O)=O)C1=CC=C(O)C=C1

Synonyms:

• 2-[2-(4-Hydroxyphenyl)acetamido]acetic acid
• 2-[[2-(4-Hydroxyphenyl)acetyl]amino]acetic acid
• Glycine, N-[(4-hydroxyphenyl)acetyl]-
• Glycine, N-[(p-hydroxyphenyl)acetyl]-
• Glycine, N-[(p-hydroxyphenyl)acetyl]-(7CI,8CI)
• Glycine,N-[(4-hydroxyphenyl)acetyl]- (9CI)
• Hydroxyphenylacetylglycine
• N-[2-(4-Hydroxyphenyl)acetyl]glycine
• [[(4-Hydroxyphenyl)acetyl]amino]acetic acid
• p-Hydroxyphenylacetylglycine
• Glycine, N-[2-(4-hydroxyphenyl)acetyl]-

2-[[2-(4-hydroxyphenyl)acetyl]amino]acetic acid

CAS: 28116-23-6

Formula: C₁₀H₁₁NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 209.1986

Ref: IN-DA00C2RR

Hydroxyphenylacetylglycine

CAS: 28116-23-6

Hydroxyphenylacetylglycine

Purity: ≥98%

Molecular weight: 209.2g/mol

Ref: 54-BUP13726

p-Hydroxyphenylacetylglycine

Controlled Product

CAS: 28116-23-6

Stability Hygroscopic
Applications p-Hydroxyphenylacetylglycine is derived from the metabolism of L-DOPA (D533751), a dopamine precursor that induces dyskinesia in Parkinson’s disease patients. p-Hydroxyphenylacetylglycine is also used as a reagent to synthesize novel piperazine salts that have antimicrobial activity against Escherichia coli and Bacillus subtilis.
References Abha, B., et al.: Pharma Chemica, 2, 446 (2010); Picconi, B., et al.: Nat. Neurosci., 6, 501 (2003)

Formula: C₁₀H₁₁NO₄

Color and Shape: Neat

Molecular weight: 209.20

Ref: TR-H950980

Hydroxyphenylacetylglycine

CAS: 28116-23-6

Hydroxyphenylacetylglycine (p-Hydroxyphenylacetylglycine) is an endogenous human metabolite.

Formula: C₁₀H₁₁NO₄

Purity: 98.73%

Color and Shape: Solid

Molecular weight: 209.2

Ref: TM-T13733

2-[[2-(4-hydroxyphenyl)acetyl]amino]acetic acid

CAS: 28116-23-6

Purity: 98%

Molecular weight: 209.201004

Ref: 10-F863465

p-Hydroxyphenylacetylglycine-13C2,15N

Controlled Product

CAS: 28116-23-6

Applications p-Hydroxyphenylacetylglycine-13C2,15N is the labelled analogue of p-Hydroxyphenylacetylglycine (H950980).

Formula: C₂C₈H₁₁₁₅NO₄

Color and Shape: Neat

Molecular weight: 212.177

Ref: TR-H950982

p-Hydroxyphenylacetylglycine

CAS: 28116-23-6

p-Hydroxyphenylacetylglycine (PHPAG) is a metabolite of creatine, which is found in urine samples. It can be detected through chemical analysis of tissue and food composition. The detection sensitivity is determined by the type of sample and the analytical method used. PHPAG has been shown to have diagnostic value for the diagnosis of certain diseases, such as liver cirrhosis, kidney disease, and fatty acid metabolism disorders. PHPAG has also been shown to be an indicator for intracellular levels of fatty acids and polyunsaturated fatty acids (PUFA).

Formula: C₁₀H₁₁NO₄

Purity: Min. 95%

Molecular weight: 209.2 g/mol

Ref: 3D-DBA11623