CAS 2812-46-6

L-Proline 1,1-dimethylethyl ester

Description:

L-Proline 1,1-dimethylethyl ester, with the CAS number 2812-46-6, is an organic compound that belongs to the class of amino acid derivatives. It is characterized by the presence of a proline backbone, which is a cyclic amino acid known for its role in protein structure and function. The compound features an ester functional group, specifically an isopropyl ester, which contributes to its chemical reactivity and solubility properties. L-Proline itself is a non-polar amino acid, and the esterification enhances its lipophilicity, making it more soluble in organic solvents. This compound is often utilized in organic synthesis and as an intermediate in the production of pharmaceuticals and agrochemicals. Its structural characteristics allow it to participate in various chemical reactions, including esterification and transesterification. Additionally, L-Proline derivatives are of interest in the field of medicinal chemistry due to their potential biological activities, including roles in enzyme catalysis and as chiral building blocks in asymmetric synthesis.

Formula: C₉H₁₇NO₂

InChI: InChI=1S/C9H17NO2/c1-9(2,3)12-8(11)7-5-4-6-10-7/h7,10H,4-6H2,1-3H3/t7-/m0/s1

InChI key: InChIKey=XJJBXZIKXFOMLP-ZETCQYMHSA-N

SMILES: C(OC(C)(C)C)(=O)[C@@H]1CCCN1

Synonyms:

• (2S)-Pyrrolidine-2-carboxylic acid tert-butyl ester
• (S)-2-(tert-Butoxycarbonyl)pyrrolidine
• (S)-Proline tert-butyl ester
• (S)-tert-Butyl pyrrolidine-2-carboxylate
• 1,1-Dimethylethyl <span class="text-smallcaps">L</span>-prolinate
• <span class="text-smallcaps">L</span>-Proline 1,1-dimethylethyl ester
• <span class="text-smallcaps">L</span>-Proline tert-butyl ester
• H-Pro-OtBu
• H-Pro-OtBu (syrup)
• L-Proline Tert-Butyl Ester
• L-Proline t-Butyl Ester
• Proline tert-butyl ester
• Proline, tert-butyl ester, <span class="text-smallcaps">L</span>-
• Tert-Butyl Prolinate
• tert-Butyl (2S)-2-pyrrolidinecarboxylate
• tert-Butyl (S)-pyrrolidine-2-carboxylate
• tert-Butyl <span class="text-smallcaps">L</span>-prolinate
• tert-butyl L-prolinate
• L-Proline, 1,1-dimethylethyl ester
• L-Proline 1,1-dimethylethyl ester

L-Proline tert-butyl ester, 98%

CAS: 2812-46-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₁₇NO₂

Purity: 98%

Molecular weight: 171.24

Ref: 02-H63657

H-Pro-OtBu (syrup)

CAS: 2812-46-6

Bachem ID: 4002617.

Formula: C₉H₁₇NO₂

Purity: > 99%

Color and Shape: Colourless

Molecular weight: 171.24

Ref: 01-4002617

H-Pro-OtBu

CAS: 2812-46-6

Formula: C₉H₁₇NO₂

Purity: 97%

Color and Shape: Liquid

Molecular weight: 171.2368

Ref: IN-DA003UKS

L-Proline tert-butyl ester

CAS: 2812-46-6

Formula: C₉H₁₇NO₂

Purity: ≥ 98.0%

Color and Shape: Clear, colourless liquid

Molecular weight: 171.2

Ref: 7W-GM7977

tert-Butyl (2S)-pyrrolidine-2-carboxylate

CAS: 2812-46-6

tert-Butyl (2S)-pyrrolidine-2-carboxylate

Formula: C₉H₁₇NO₂

Purity: 98%

Color and Shape: clear. colourless liquid

Molecular weight: 171.24g/mol

Ref: 54-OR61281

L-Proline tert-butyl ester

CAS: 2812-46-6

L-Proline tert-butyl ester is an organic compound that is used in the synthesis of amino acids and pharmaceuticals. It is chiral, and can be synthesized by a stepwise, asymmetric synthesis. The hydrochloric acid treatment of L-lysine with trifluoroacetic acid yields the corresponding L-proline tert-butyl ester. The stereoselectivity of this process depends on the type of catalyst used for demethylation and alkylation reactions.

Formula: C₉H₁₇NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 171.24 g/mol

Ref: 3D-FP47582

H-Pro-OtBu

CAS: 2812-46-6

M02955 - H-Pro-OtBu

Formula: C₉H₁₇NO₂

Purity: 97%

Color and Shape: Liquid

Molecular weight: 171.24

Ref: 10-M02955

L-Proline tert-Butyl Ester

Controlled Product

CAS: 2812-46-6

Applications L-Proline tert-Butyl Ester is a tert-Butyl ester of L-Proline (P755995) which is an amino acid and precursor (with vitamin C) for collagen, the building block of the structure of tendons, ligaments, arteries, veins and muscles. It is important in wound healing.
References Bondarenko, L.B., et al.: Int. J. Peptides., 2, 1687 (2012); Rimer, T., et al.: Biomacromolecules, 13, 2110 (2012);

Formula: C₁₉H₂₈O₃

Color and Shape: Neat

Molecular weight: 304.424

Ref: TR-P755870