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CAS 2813310-07-3

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  • KH-4-43

    CAS:
    <p>KH-4-43, an inhibitor of the E3 CRL4 ligase complex, demonstrates anticancer activity by targeting the core of the E3 CRL4. It exhibits a binding affinity (Kd) of 83 nM to the E3 ROC1-CUL4A CTD and 9.4 μM to the closely related ROC1-CUL1 CTD [1].</p>
    Formula:C19H10ClF3N2O4
    Color and Shape:Solid
    Molecular weight:422.74