
CAS 2813310-07-3
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KH-4-43
CAS:<p>KH-4-43, an inhibitor of the E3 CRL4 ligase complex, demonstrates anticancer activity by targeting the core of the E3 CRL4. It exhibits a binding affinity (Kd) of 83 nM to the E3 ROC1-CUL4A CTD and 9.4 μM to the closely related ROC1-CUL1 CTD [1].</p>Formula:C19H10ClF3N2O4Color and Shape:SolidMolecular weight:422.74
