CAS 281655-37-6

(3S)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]morpholine-3-carboxylic acid

Description:

The chemical substance known as (3S)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]morpholine-3-carboxylic acid, with the CAS number 281655-37-6, is a synthetic organic compound characterized by its morpholine core structure, which is a six-membered ring containing both nitrogen and oxygen atoms. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, commonly used in peptide synthesis to protect amino groups during the formation of peptide bonds. The presence of the carboxylic acid functional group indicates that it can participate in acid-base reactions and may serve as a precursor for further chemical modifications. The stereochemistry at the morpholine ring is specified as (3S), indicating a specific spatial arrangement of its substituents, which can influence its biological activity and interactions. Overall, this compound is of interest in medicinal chemistry and peptide synthesis due to its structural features and potential applications in drug development.

Formula: C₂₀H₁₉NO₅

InChI: InChI=1/C20H19NO5/c22-19(23)18-12-25-10-9-21(18)20(24)26-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17-18H,9-12H2,(H,22,23)/t18-/m0/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=O)N1CCOC[C@H]1C(=O)O

Synonyms:

• (S)-Fmoc-2-Carboxymorpholine
• 4-FMoc-3(S)-Morpholine carboxylic acid
• (S)-4-N-FMoc-3-Morpholinecarboxylic acid
• (3S)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]morpholine-3-carbox...
• (S)-4-Fmoc-3-morpholinecarboxylicacid
• (S)-N-(9-FLUORENYLMETHYLOXYCARBONYL)-MORPHOLINE-3-CARBOXYLIC ACID
• N-FMOC-MORPOLINE[(3S)-COOH]
• (3S)-3,4-Morpholinedicarboxylic acid 4-(9H-fluoren-9-ylmethyl) ester
• 3,4-Morpholinedicarboxylic acid, 4-(9H-fluoren-9-ylmethyl) ester, (3S)-
• (S)-4-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)MORPHOLINE-3-CARBOXYLIC ACID
• FMOC-S-MORPH-OH
• FMOC-S-MO3C-OH
• (S)-FMOC-3-CARBOXYMORPHOLINE

(S)-Fmoc-3-carboxymorpholine

CAS: 281655-37-6

Formula: C₂₀H₁₉NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 353.3686

Ref: IN-DA00BD5R

(S)-4-(((9H-Fluoren-9-yl)methoxy)carbonyl)morpholine-3-carboxylic acid

CAS: 281655-37-6

(S)-4-(((9H-Fluoren-9-yl)methoxy)carbonyl)morpholine-3-carboxylic acid

Purity: 99%

Molecular weight: 353.37g/mol

Ref: 54-OR80836

(S)-4-N-Fmoc-3-morpholinecarboxylic acid

CAS: 281655-37-6

Formula: C₂₀H₁₉NO₅

Purity: 97%

Color and Shape: Liquid, No data available.

Molecular weight: 353.374

Ref: 10-F494214

4-Fmoc-3(S)-morpholinecarboxylic Acid

Controlled Product

CAS: 281655-37-6

Applications 4-Fmoc-3(S)-morpholinecarboxylic Acid is used to prepare heterocyclic core analogs of a direct thrombin inhibitor.
References Blizard, T., et al.: Bioorg. Med. Chem.Lett., 24, 1111 (2014)

Formula: C₂₀H₁₉NO₅

Color and Shape: Neat

Molecular weight: 353.37

Ref: TR-F648485