CAS 2820-55-5

Nicotine N-oxide

Description:

Nicotine N-oxide is a chemical compound derived from nicotine, which is primarily known for its presence in tobacco. It is characterized by its molecular structure, where an oxygen atom is bonded to the nitrogen atom of the nicotine molecule, resulting in a quaternary ammonium compound. This modification alters its pharmacological properties compared to nicotine. Nicotine N-oxide is typically a white to off-white solid and is soluble in water and organic solvents. It exhibits a relatively stable nature under standard conditions but can undergo further reactions under specific circumstances. The compound is of interest in pharmacology and toxicology, as it may play a role in the metabolism of nicotine and its effects on the human body. Additionally, it has been studied for its potential implications in addiction and neuropharmacology. As with many nitrogen-containing compounds, it may exhibit basic properties, and its behavior in biological systems can vary significantly from that of its parent compound, nicotine.

Formula: C₁₀H₁₄N₂O

InChI: InChI=1S/C10H14N2O/c1-11-6-3-5-10(11)9-4-2-7-12(13)8-9/h2,4,7-8,10H,3,5-6H2,1H3/t10-/m0/s1

InChI key: InChIKey=YHXKVHQFWVYXIC-JTQLQIEISA-N

SMILES: CN1[C@H](C2=CN(=O)=CC=C2)CCC1

Synonyms:

• 3-(1-Methyl-2-pyrrolidinyl)pyridine, N-oxide
• 3-[(2S)-1-Methylpyrrolidin-2-yl]pyridin-1-ium-1-olate
• Nicotine 1-N-oxide
• Nicotine N-oxide
• Nicotine, 1-oxide
• Pyridine, 3-(1-Methyl-2-Pyrrolidinyl)-, 1-Oxide
• Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, 1-oxide, (S)-
• Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, N-oxide, (2s)-
• Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, 1-oxide
• 3-(1-Methylpyrrolidin-2-yl)pyridine 1-oxide

3-(1-methyl-2-pyrrolidinyl)pyridinium-1-olate

CAS: 2820-55-5

3-(1-methyl-2-pyrrolidinyl)pyridinium-1-olate

Purity: ≥95%

Molecular weight: 178.23g/mol

Ref: 54-OR24892

Nicotine N-oxide

CAS: 2820-55-5

Formula: C₁₀H₁₄N₂O

Molecular weight: 178.24

Ref: 4Z-N-06119

(2'S)-Nicotine 1-Oxide

CAS: 2820-55-5

Formula: C₁₀H₁₄N₂O

Color and Shape: Yellow

Molecular weight: 178.23

Ref: TR-N428000

(2'S)-Nicotine 1-Oxide-d4

Controlled Product

CAS: 2820-55-5

Formula: C₁₀D₄H₁₀N₂O

Color and Shape: Neat

Molecular weight: 182.256

Ref: TR-N428002

(2'S)-Nicotine 1-oxide

CAS: 2820-55-5

(2'S)-Nicotine 1-oxide is a nicotinic acetylcholine receptor agonist that acts as an insecticide. It is used on plants to control aphids, thrips, and other pests. The effects of (2'S)-nicotine 1-oxide on animals are not well studied. This compound is marketed as a dietary supplement for weight loss, although there has been no validation of this claim. The matrix effect of this drug can cause interference in the analysis of urine samples. Nuclear DNA can be used to detect the presence of (2'S)-nicotine 1-oxide in cancer tissue. Analytical methods for quantifying (2'S)-nicotine 1-oxide include gas chromatography with mass spectrometry detection (GC/MS), liquid chromatography with tandem mass spectrometry detection (LC/MS/MS), and liquid chromatography with ultraviolet detection (LC/UV).

Formula: C₁₀H₁₄N₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 178.23 g/mol

Ref: 3D-FN26202

(2'S)-Nicotine-1-oxide

CAS: 2820-55-5

(2'S)-Nicotine-1-oxide, a nicotine metabolite, arises from the liver's metabolism of nicotine via the cytochrome P450 (CYP) isoform CYP2A6. It has been identified in human sperm and semen.

Formula: C₁₀H₁₄N₂O

Color and Shape: Solid

Molecular weight: 178.235

Ref: TM-T85296