CAS 282101-98-8

2-Chloro-5-nitropyrimidin-4(1H)-one

CAS: 282101-98-8

2-Chloro-5-nitropyrimidin-4(1H)-one

Purity: 95%

Molecular weight: 175.53g/mol

Ref: 54-OR1065072

2-Chloro-5-nitropyrimidin-4-ol

Controlled Product

CAS: 282101-98-8

Applications 2-Chloro-5-nitropyrimidin-4-ol is an intermediate used in the synthesis of 4-Chloro-5-nitro-2-(propylthio)pyrimidine (C374095), which is an impurity of the drug Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).
References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)

Formula: C₄H₂ClN₃O₃

Color and Shape: Neat

Molecular weight: 175.53

Ref: TR-C371411