CAS 282101-98-8

Formula: C4H2ClN3O3

InChI: InChI=1S/C4H2ClN3O3/c5-4-6-1-2(8(10)11)3(9)7-4/h1H,(H,6,7,9)

InChI key: YAWXGRKOOLHJSP-UHFFFAOYSA-N

SMILES: C1=C(C(=O)NC(=N1)Cl)[N+](=O)[O-]

2-Chloro-5-nitropyrimidin-4(1H)-one

CAS: 282101-98-8

2-Chloro-5-nitropyrimidin-4(1H)-one

Formula: C₄H₂ClN₃O₃

Purity: 95+%

Molecular weight: 175.53

Ref: 54-OR1065072

2-Chloro-5-nitropyrimidin-4(1H)-one

CAS: 282101-98-8

Purity: 95%

Ref: IN-DA024KTH

2-Chloro-5-nitropyrimidin-4(1H)-one

CAS: 282101-98-8

2-Chloro-5-nitropyrimidin-4(1H)-one

Formula: C₄H₂ClN₃O₃

Purity: 95+%

Molecular weight: 175.53

Ref: IN-DG00734915

2-Chloro-5-nitropyrimidin-4-ol

Controlled Product

CAS: 282101-98-8

Applications 2-Chloro-5-nitropyrimidin-4-ol is an intermediate used in the synthesis of 4-Chloro-5-nitro-2-(propylthio)pyrimidine (C374095), which is an impurity of the drug Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).
References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)

Formula: C₄H₂ClN₃O₃

Color and Shape: Neat

Molecular weight: 175.53

Ref: TR-C371411