CB2R/5-HT1AR agonist 1, identified by its CAS number 2821085-76-9, is a chemical compound that acts as an agonist for both the cannabinoid receptor type 2 (CB2R) and the serotonin receptor type 1A (5-HT1AR). This dual activity suggests potential therapeutic applications in areas such as pain management, anxiety, and mood disorders, as both receptors are involved in modulating these physiological processes. The compound's structure likely features functional groups that facilitate binding to these receptors, promoting their activation. Additionally, its pharmacological profile may include properties such as selectivity, potency, and efficacy, which are critical for determining its suitability for research or clinical use. As with many receptor agonists, understanding its pharmacokinetics, including absorption, distribution, metabolism, and excretion (ADME), is essential for evaluating its potential as a therapeutic agent. Further studies would be necessary to elucidate its safety, side effects, and overall impact on biological systems.

CB2R/5-HT1AR agonist 1

2821085-76-9: CB2R/5-HT1AR agonist 1, identified by its CAS number 2821085-76-9, is a chemical compound that acts as an agonist for both the cannabinoid receptor type 2 (CB2R) and the serotonin receptor type 1A (5-HT1AR). This dual activity suggests potential therapeutic applications in areas such as pain management, anxiety, and mood disorders, as both receptors are involved in modulating these physiological processes. The compound's structure likely features functional groups that facilitate binding to these receptors, promoting their activation. Additionally, its pharmacological profile may include properties such as selectivity, potency, and efficacy, which are critical for determining its suitability for research or clinical use. As with many receptor agonists, understanding its pharmacokinetics, including absorption, distribution, metabolism, and excretion (ADME), is essential for evaluating its potential as a therapeutic agent. Further studies would be necessary to elucidate its safety, side effects, and overall impact on biological systems.

<p>Compound 2o, also known as CB2R/5-HT1AR agonist 1, serves as a partial orally active agonist for the CB2 receptor (EC50 = 479.6 nM) and a full agonist for the 5-HT1A receptor (EC50 = 2.7 μM). This compound demonstrates both anti-anxiety and anti-depressive effects and has favorable pharmacokinetic properties [1].</p>

CAS 2821085-76-9

CB2R/5-HT1AR agonist 1

CB2R/5-HT1AR agonist 1

Ref: TM-T86012