CAS 283584-52-1

5-Fluoro-3-hydrazonoindolin-2-one

Description:

5-Fluoro-3-hydrazonoindolin-2-one is a chemical compound characterized by its unique structure, which includes an indolinone core with a hydrazone functional group and a fluorine substituent. This compound typically exhibits a solid-state form and is known for its potential biological activity, making it of interest in medicinal chemistry. The presence of the fluorine atom can enhance lipophilicity and influence the compound's pharmacokinetic properties. The hydrazone moiety may contribute to its reactivity and ability to form hydrogen bonds, which can be crucial for interactions with biological targets. Additionally, the compound may display various physical properties such as solubility in organic solvents, which can vary based on the specific conditions. Its synthesis often involves multi-step organic reactions, and it may serve as a precursor or intermediate in the development of more complex pharmaceuticals. Overall, 5-Fluoro-3-hydrazonoindolin-2-one represents a class of compounds that are valuable for research in drug discovery and development.

Formula: C₈H₆FN₃O

InChI: InChI=1/C8H6FN3O/c9-4-1-2-6-5(3-4)7(12-10)8(13)11-6/h1-3H,10H2,(H,11,12,13)

SMILES: c1cc2c(cc1F)C(=NN)C(=O)N2

Synonyms:

• 1H-indole-2,3-dione, 5-fluoro-, 3-hydrazone
• 5-Fluoro-3-hydrazono-1,3-dihydro-2H-indol-2-one
• 5-fluoro-3-hydrazinyl-2H-indol-2-one
• 5-Fluoro-3-Hydrazonoeindolin-2-One

5-Fluoro-3-hydrazonoindolin-2-one

CAS: 283584-52-1

Formula: C₈H₆FN₃O

Purity: 96%

Color and Shape: Solid

Molecular weight: 179.1511

Ref: IN-DA00383Y

5-Fluoro-3-hydrazonoindolin-2-one

CAS: 283584-52-1

5-Fluoro-3-hydrazonoindolin-2-one

Purity: 96%

Ref: 54-PC1001359

Sunitinib Impurity 21

CAS: 283584-52-1

Formula: C₈H₆FN₃O

Molecular weight: 179.15

Ref: 4Z-S-4136

5-​Fluoro-1H-​indole-​2,​3-​dione 3-​Hydrazone

Controlled Product

CAS: 283584-52-1

Formula: C₈H₆FN₃O

Color and Shape: Neat

Molecular weight: 179.151

Ref: TR-F595445

5-Fluoro-3-hydrazonoindolin-2-one

CAS: 283584-52-1

Purity: 96%

Molecular weight: 179.154

Ref: 10-F986919

5-Fluoro-3-hydrazonoindolin-2-one

CAS: 283584-52-1

5-Fluoro-3-hydrazonoindolin-2-one is an organic compound that can be synthesized using ethyl acetate as a solvent and formylation with malate. This process is scalable and offers high yields. The reaction time for this synthesis is relatively short, making it ideal for industrialization. 5-Fluoro-3-hydrazonoindolin-2-one can also be used to synthesize sunitinib, which is an experimental drug used to treat cancer. Sunitinib has been shown to inhibit the growth of cancer cells by interfering with the activity of proteins involved in cell proliferation, cell cycle progression, and cellular differentiation.

Formula: C₈H₆FN₃O

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 179.15 g/mol

Ref: 3D-FF46834