As of my last update in October 2023, there is limited publicly available information on the chemical substance known as "KT-333 ammonium" with the CAS number 2839758-34-6. This compound may be a specialized or proprietary chemical, potentially used in specific industrial or research applications. Generally, ammonium compounds are characterized by the presence of the ammonium ion (NH4+), which can exhibit properties such as solubility in water, the ability to act as a weak base, and potential roles in various chemical reactions. The specific characteristics of KT-333 ammonium, including its physical state, reactivity, and safety profile, would depend on its molecular structure and functional groups. For precise details, including its applications, toxicity, and handling procedures, consulting safety data sheets (SDS) or scientific literature specific to this compound is recommended. Always ensure to follow appropriate safety guidelines when working with chemical substances.

KT-333 ammonium

2839758-34-6: As of my last update in October 2023, there is limited publicly available information on the chemical substance known as "KT-333 ammonium" with the CAS number 2839758-34-6. This compound may be a specialized or proprietary chemical, potentially used in specific industrial or research applications. Generally, ammonium compounds are characterized by the presence of the ammonium ion (NH4+), which can exhibit properties such as solubility in water, the ability to act as a weak base, and potential roles in various chemical reactions. The specific characteristics of KT-333 ammonium, including its physical state, reactivity, and safety profile, would depend on its molecular structure and functional groups. For precise details, including its applications, toxicity, and handling procedures, consulting safety data sheets (SDS) or scientific literature specific to this compound is recommended. Always ensure to follow appropriate safety guidelines when working with chemical substances.

<p>KT-333 ammonium (Compound A) acts as a molecular glue that targets and promotes the degradation of the STAT3 protein through the ubiquitin-proteasome system. This compound achieves selective degradation by binding simultaneously to the STAT3 protein and the E3 ubiquitin ligase von Hippel-Lindau protein (VHL). It exhibits strong selectivity and efficacy in degrading STAT3, possessing notable antitumor properties. KT-333 ammonium is particularly useful for research on hematologic malignancies, including large granular lymphocytic leukemia (LGL-L), peripheral T-cell lymphoma (PTCL), and cutaneous T-cell lymphoma (CTCL) [1].</p>

CAS 2839758-34-6

KT-333 ammonium

KT-333 ammonium

Ref: TM-T86788