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CAS 2841467-86-3

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  • IDO1-IN-25

    CAS:
    <p>IDO1-IN-25, a dual inhibitor of IDO1/TDO2, showcases IC50 values of 0.17 μM for IDO1 and 3.2 μM for TDO2. It effectively suppresses NO production in RAW264.7 cells following stimulation with lipopolysaccharide (LPS). Additionally, IDO1-IN-25 demonstrates anti-inflammatory properties in a mouse ear edema model of acute inflammation induced by croton oil.</p>
    Formula:C14H8Cl3NO2S
    Color and Shape:Solid
    Molecular weight:360.64