CAS 28416-82-2: 6α,9α-Difluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic acid

Description: 6α,9α-Difluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic acid, with CAS number 28416-82-2, is a synthetic steroid compound that exhibits characteristics typical of glucocorticoids. This compound features a complex steroid structure, characterized by multiple functional groups, including fluorine atoms, hydroxyl groups, and a carboxylic acid moiety. The presence of fluorine enhances its biological activity and stability, while the hydroxyl groups contribute to its solubility and interaction with biological receptors. The methyl group at the 16α position and the keto group at the 3 position are significant for its pharmacological properties. This compound is primarily studied for its potential anti-inflammatory and immunosuppressive effects, making it relevant in therapeutic applications. Its structural modifications allow for selective receptor binding, which can influence its efficacy and side effect profile. Overall, this compound represents a class of steroids that are crucial in medical chemistry for developing treatments for various inflammatory and autoimmune conditions.

Formula: C₂₁H₂₆F₂O₅

InChI: InChI=1S/C21H26F2O5/c1-10-6-12-13-8-15(22)14-7-11(24)4-5-18(14,2)20(13,23)16(25)9-19(12,3)21(10,28)17(26)27/h4-5,7,10,12-13,15-16,25,28H,6,8-9H2,1-3H3,(H,26,27)/t10-,12+,13+,15+,16+,18+,19+,20+,21+/m1/s1

InChI key: InChIKey=QSVBUQTYFQFEHC-IDIDPBNYSA-N

SMILES: O=C1C=CC2(C(=C1)C(F)CC3C4CC(C)C(O)(C(=O)O)C4(C)CC(O)C32F)C

Synonyms:

• 11β,17α-Dihydroxy-6α,9α-difluoro-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic acid
• 6α,9α-Difluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic acid
• 6α,9α-Difluoro-11β,17α-dihydroxy-16α-methylpregna-3-oxo-1,4-diene-17β-carboxylic acid
• Androsta-1,4-Diene-17-Carboxylic Acid, 6,9-Difluoro-11,17-Dihydroxy-16-Methyl-3-Oxo-, (6Α,11Β,16Α,17Α)-
• Androsta-1,4-diene-17β-carboxylic acid, 6α,9-difluoro-11β,17-dihydroxy-16α-methyl-3-oxo-
• Flumethasone acid
• (6α,11β,16α,17α)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid

Fluticasone Propionate Related Compound J (6α, 9α-difluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic acid)

CAS: 28416-82-2

Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc not elsewhere specified …

• Formula: C₂₁H₂₆F₂O₅
• Color and Shape: White Light Yellow Crystalline Solid
• Molecular weight: 396.17483

Androsta-1,4-diene-17-carboxylic acid,6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, (6a,11b,16a,17a)-

CAS: 28416-82-2

• Formula: C₂₁H₂₆F₂O₅
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 396.4249

Fluticasone 17β-Carboxylic Acid

CAS: 28416-82-2

Fluticasone 17β-carboxylic acid is an intermediate in the synthesis of the glucocorticosteroid fluticasone propionate .1

• Formula: C₂₁H₂₆F₂O₅
• Color and Shape: Solid
• Molecular weight: 396.42

Fluticasone 17-β-Carboxylic Acid

CAS: 28416-82-2

• Formula: C₂₁H₂₆F₂O₅
• Color and Shape: White To Off-White Solid
• Molecular weight: 396.43

6α,9α-Difluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic Acid

CAS: 28416-82-2

• Formula: C₂₁H₂₆F₂O₅
• Color and Shape: Neat
• Molecular weight: 396.42

Fluticasone 17β-Carboxylic Acid

CAS: 28416-82-2

• Formula: C₂₁H₂₆F₂O₅
• Color and Shape: White To Off-White
• Molecular weight: 396.42

Fluticasone 17b-carboxylic acid

CAS: 28416-82-2

Please enquire for more information about Fluticasone 17b-carboxylic acid including the price, delivery time and …

• Formula: C₂₁H₂₆F₂O₅
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 396.42 g/mol

Fluticasone-d3 17β-Carboxylic Acid

CAS: 28416-82-2

• Formula: C₂₁H₂₃D₃F₂O₅
• Color and Shape: Neat
• Molecular weight: 399.44