CAS 28416-84-4

Androsta-1,4-diene-17-carboxylic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, methyl ester, (6α,11β,16α,17α)-

Description:

Androsta-1,4-diene-17-carboxylic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, methyl ester, with the CAS number 28416-84-4, is a synthetic steroid derivative characterized by its complex structure, which includes multiple functional groups such as carboxylic acid, hydroxyl, and ester moieties. This compound features a steroid backbone, typical of androgens, with specific substitutions that enhance its biological activity. The presence of fluorine atoms contributes to its lipophilicity and may influence its receptor binding affinity and metabolic stability. The stereochemistry indicated by the (6α,11β,16α,17α) configuration suggests specific spatial arrangements that are crucial for its interaction with biological targets. This compound is often studied for its potential applications in pharmacology, particularly in the context of hormone regulation and therapeutic interventions in conditions related to steroid hormones. Its unique properties make it a subject of interest in medicinal chemistry and endocrinology research.

Formula: C₂₂H₂₈F₂O₅

InChI: InChI=1S/C22H28F2O5/c1-11-7-13-14-9-16(23)15-8-12(25)5-6-19(15,2)21(14,24)17(26)10-20(13,3)22(11,28)18(27)29-4/h5-6,8,11,13-14,16-17,26,28H,7,9-10H2,1-4H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1

InChI key: InChIKey=HTJSTTZFHWMHDB-GQKYHHCASA-N

SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(OC)=O)(O)[C@H](C)C3)[H])(C[C@H](F)C=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

• Androsta-1,4-diene-17-carboxylic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, methyl ester, (6α,11β,16α,17α)-
• Androsta-1,4-diene-17β-carboxylic acid, 6α,9-difluoro-11β,17-dihydroxy-16α-methyl-3-oxo-, methyl ester

Fluticasone Impurity 56

CAS: 28416-84-4

Formula: C₂₂H₂₈F₂O₅

Molecular weight: 410.46

Ref: 4Z-F-0989