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CAS 2845188-22-7

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Methanesulfonamide, N-[6-[[5-bromo-2-[[5-ethyl-2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-4-pyrimidinyl]amino]-2,3-dihydro-1,4-benzodioxin-5-yl]-N-methyl-

Formula:C33H45BrN8O5S
Synonyms:
  • Methanesulfonamide, N-[6-[[5-bromo-2-[[5-ethyl-2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-4-pyrimidinyl]amino]-2,3-dihydro-1,4-benzodioxin-5-yl]-N-methyl-
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  • WZH-15-125
    Targetmol
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    WZH-15-125

    CAS:
    WZH-15-125 is a potent ALK inhibitor capable of overcoming resistance, particularly with complex ALK mutations. It exhibits an IC50 of 101.7 nM against the highly recalcitrant Lorlatinib-resistant G1202R/L1196M mutation. Additionally, WZH-15-125 can serve as a PROTAC target protein ligand for synthesizing PROTACWZH-17-002. This compound is applicable in non-small cell lung cancer research.
    Formula:C33H45BrN8O5S
    Color and Shape:Solid
    Molecular weight:745.73

    Ref: TM-T210936