CAS 2847881-42-7

5,6,7,8-Tetrahydro-7-(8-methyl-1-naphthalenyl)-4-[(2R)-2-methyl-1-piperazinyl]-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidine

Description:

5,6,7,8-Tetrahydro-7-(8-methyl-1-naphthalenyl)-4-[(2R)-2-methyl-1-piperazinyl]-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidine, identified by its CAS number 2847881-42-7, is a complex organic compound characterized by its multi-cyclic structure and various functional groups. This substance features a pyrido[3,4-d]pyrimidine core, which is a bicyclic structure known for its biological activity. The presence of multiple rings, including a tetrahydro component and naphthalene moiety, contributes to its potential pharmacological properties. The compound also contains piperazine and pyrrolidine substituents, which are often associated with enhanced solubility and bioactivity. Its stereochemistry, indicated by the (2R) and (2S) designations, suggests specific spatial arrangements that can influence its interaction with biological targets. Overall, this compound may exhibit significant interest in medicinal chemistry, particularly in the development of therapeutic agents, although specific biological activities and applications would require further investigation and validation through empirical studies.

Formula: C₂₉H₃₈N₆O

Synonyms:

• 5,6,7,8-Tetrahydro-7-(8-methyl-1-naphthalenyl)-4-[(2R)-2-methyl-1-piperazinyl]-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidine
• TH-Z816

TH-Z816

CAS: 2847881-42-7

TH-Z816 acts as a reversible inhibitor targeting the KRAS(G12D) mutation, exhibiting an IC50 of 14 µM. This compound is utilized in cancer research [1].

Formula: C₂₉H₃₈N₆O

Color and Shape: Solid

Molecular weight: 486.65

Ref: TM-T87525