CAS 2848-25-1

2-hydroxyphenyl acetate

Description:

2-Hydroxyphenyl acetate, also known as salicylate acetate, is an organic compound characterized by its ester functional group derived from salicylic acid and acetic acid. It features a hydroxyl group (-OH) attached to a phenyl ring, which contributes to its reactivity and solubility properties. This compound typically appears as a colorless to pale yellow liquid with a pleasant, sweet aroma, making it of interest in the fragrance and flavor industries. Its molecular structure allows for hydrogen bonding, which influences its solubility in polar solvents like water and organic solvents. 2-Hydroxyphenyl acetate exhibits moderate stability under standard conditions but may undergo hydrolysis in the presence of strong acids or bases. It is also known for its potential applications in pharmaceuticals, particularly as a precursor in the synthesis of various medicinal compounds. Safety data indicates that, while it may cause irritation upon contact with skin or eyes, it is generally considered to have low toxicity. Proper handling and storage are recommended to ensure safety and maintain its integrity.

Formula: C₈H₈O₃

InChI: InChI=1/C8H8O3/c1-6(9)11-8-5-3-2-4-7(8)10/h2-5,10H,1H3

Synonyms:

• Catechol, acetate
• 1,2-benzenediol, monoacetate

2-Hydroxyphenyl acetate

CAS: 2848-25-1

2-Hydroxyphenyl acetate (2HPA) is a phenolic compound that has been shown to inhibit the growth of prostate cancer cells in vitro. 2HPA inhibits the activity of two enzymes, hydroxylase and transketolase, which are involved in energy metabolism and collagen synthesis. 2HPA also induces apoptosis in prostate cancer cells by activating caspases and inhibiting DNA synthesis. Studies have shown that 2HPA may be effective against fungal infections by inhibiting cell growth. This compound also has anti-inflammatory properties and may be beneficial for those with osteoporosis by stimulating the production of new bone cells. 2HPA has been shown to stimulate the release of neurotransmitters, such as acetylcholine, glutamate, GABA, dopamine, norepinephrine and serotonin from mouse hippocampal neurons. It also inhibits the phosphorylation of cyclic AMP response element binding protein (CREB) to block CREB-mediated

Formula: C₈H₈O₃

Purity: Min. 95%

Molecular weight: 152.15 g/mol

Ref: 3D-CAA84825