CAS 2848-96-6
:Lorazepam acetate
Description:
Lorazepam acetate, with the CAS number 2848-96-6, is a derivative of lorazepam, a medication belonging to the benzodiazepine class. It is primarily characterized by its sedative, anxiolytic, and anticonvulsant properties, making it useful in the treatment of anxiety disorders, insomnia, and seizure management. The compound exhibits a high affinity for the GABA-A receptor, enhancing the inhibitory effects of the neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous system. Lorazepam acetate is typically administered in its acetate form to improve solubility and bioavailability. It is a white to off-white crystalline powder, relatively stable under normal conditions, and is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO). The pharmacokinetics of lorazepam acetate involve rapid absorption and distribution, with a moderate half-life, allowing for effective management of acute anxiety episodes. As with other benzodiazepines, caution is advised due to the potential for dependence and withdrawal symptoms with prolonged use.
Formula:C17H12Cl2N2O3
InChI:InChI=1/C17H12Cl2N2O3/c1-9(22)24-17-16(23)20-14-7-6-10(18)8-12(14)15(21-17)11-4-2-3-5-13(11)19/h2-8,17H,1H3,(H,20,23)
InChI key:InChIKey=CYDZMDOLVUBPNL-UHFFFAOYSA-N
SMILES:ClC1=C(C=2C=3C(NC(=O)C(OC(C)=O)N2)=CC=C(Cl)C3)C=CC=C1
Synonyms:- 2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, acetate
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, acetate (ester)
- 3-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- 3-Acetoxy-7-chloro-5-(o-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- 7-chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl acetate
- Lorazepam acetate
- Ro 7-8407
- 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-2-oxo-2H-1,4-benzodiazepin-3-yl acetate
- [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] ethanoate
- Acetic acid [7-chloro-5-(2-chlorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepin]-3-yl ester
- acetic acid [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] ester
- CYDZMDOLVUBPNL-UHFFFAOYSA-N
- Lorazepam USP Related Compound A
- Lorazepam 3-acetate
- Lorazepam Related Compound A (25 mg) (7-Chloro-5-(ochlorophenyl)-1,3-dihydro-3-acetoxy-2H-1,4-benzodiazepin-2-one)
- Lorazepam Related Compound A (7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-acetoxy-2H-1,4-benzodiazepi (1370327)
- LorazepaM Related CoMpound A
- [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] acetate
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Found 8 products.
Lorazepam Acetate ((3RS)-7-Chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl Acetate)
CAS:Controlled ProductColor and Shape:NeatLorazepam Acetate ((3RS)-7-Chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl Acetate) 0.1 mg/ml in Acetonitrile
CAS:Controlled ProductColor and Shape:Single SolutionLorazepam Related Compound A (7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-acetoxy-2H-1,4-benzodiazepin-2-one)
CAS:Drugs with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoiFormula:C17H12Cl2N2O3Color and Shape:Off-White PowderMolecular weight:362.0225(3RS)-7-Chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-ylAcetate (Lorazepam Acetate)
CAS:Controlled ProductColor and Shape:NeatLorazepam Acetate
CAS:Controlled ProductFormula:C17H12Cl2N2O3Color and Shape:NeatMolecular weight:363.193-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
CAS:Controlled Product<p>3-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one is a drug that binds to human serum albumin. It is an enantiomer of lorazepam and is a specific ligand for α1 acid glycoprotein. This compound has been shown to be effective in the treatment of epilepsy and benzodiazepine withdrawal syndrome. It also has a cavity that can be used to bind reactive molecules such as carbamazepine. 3-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin--2--one has been shown to have antitumour effects on cultured cells by inhibiting protein synthesis, thus leading to cell death.</p>Formula:C17H12Cl2N2O3Purity:Min. 95%Color and Shape:PowderMolecular weight:363.19 g/mol2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-
CAS:Formula:C17H12Cl2N2O3Molecular weight:363.1948
