CAS 28485-17-8

Ethyl 1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylate

Description:

Ethyl 1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylate, with the CAS number 28485-17-8, is a chemical compound that belongs to the class of pyrimidine derivatives. It features a pyrimidine ring that is substituted with a carboxylate group and contains two carbonyl groups, contributing to its dioxo functionality. This compound is typically characterized by its solid state at room temperature and exhibits moderate solubility in polar solvents due to the presence of the carboxylate group. Ethyl 1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylate may be of interest in medicinal chemistry and organic synthesis, potentially serving as an intermediate in the synthesis of various bioactive compounds. Its structural features suggest that it may participate in various chemical reactions, including nucleophilic substitutions and cyclization processes. As with many organic compounds, handling should be conducted with care, observing appropriate safety protocols to mitigate any risks associated with its use.

Formula: C₇H₈N₂O₄

InChI: InChI=1S/C7H8N2O4/c1-2-13-6(11)4-3-8-7(12)9-5(4)10/h3H,2H2,1H3,(H2,8,9,10,12)

InChI key: InChIKey=MKNYHTGOVKPZMU-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C=1C(=O)NC(=O)NC1

Synonyms:

• 2,4-Dihydroxypyrimidine-5-carboxylic acid ethyl ester
• 5-Carbethoxyuracil
• 5-Ethoxycarbonyluracil
• 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, ethyl ester
• Ethyl 1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylate
• Ethyl 2,4-Dihydroxypyrimidine-5-Carboxylate
• Ethyl 2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
• Ethyl 4-Hydroxy-2-Oxo-1,2-Dihydropyrimidine-5-Carboxylate
• Ethyluracil-5-carboxylate
• NSC 513173
• Uracil-5-carboxylic acid ethyl ester

Ethyl uracil-5-carboxylate, 98%

CAS: 28485-17-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₈N₂O₄

Purity: 98%

Color and Shape: White to cream, Powder

Molecular weight: 184.15

Ref: 02-H26507

Ethyl Uracil-5-carboxylate

CAS: 28485-17-8

Formula: C₇H₈N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 184.1494

Ref: IN-DA002VH5

5-Carbethoxyuracil

CAS: 28485-17-8

5-Carbethoxyuracil

Purity: 98%

Molecular weight: 184.15g/mol

Ref: 54-OR322325

5-Carbethoxyuracil

CAS: 28485-17-8

Formula: C₇H₈N₂O₄

Molecular weight: 184.15

Ref: 7W-GL0927

Ethyl4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate

CAS: 28485-17-8

Formula: C₇H₈N₂O₄

Purity: 95%

Molecular weight: 184.151

Ref: 10-F092561

5-Carbethoxyuracil

CAS: 28485-17-8

5-Carbethoxyuracil (5CBU) is an inhibitor of uridine phosphorylase, which catalyzes the conversion of uridine to 5-formyluracil. 5CBU is a potential drug candidate for the treatment of toxoplasmosis. It has shown activity against a mutant strain of toxoplasma that is resistant to orotic acid and acetonitrile. Inhibition data shows that it blocks the production of orotic acid and 5-formyluracil, both of which are intermediates in the biosynthesis pathway.

Formula: C₇H₈N₂O₄

Purity: Min. 95%

Color and Shape: White To Off-White Solid

Molecular weight: 184.15 g/mol

Ref: 3D-FC07975