CAS 28526-44-5

3,3',19-trihydroxy-4',5'-didehydro-5',6',7,8-tetrahydro-beta,beta-caroten-8-one

Description:

3,3',19-Trihydroxy-4',5'-didehydro-5',6',7,8-tetrahydro-beta,beta-caroten-8-one, with CAS number 28526-44-5, is a carotenoid derivative characterized by its complex polyene structure, which includes multiple hydroxyl groups and a keto group. This compound exhibits strong antioxidant properties due to its ability to scavenge free radicals, making it of interest in various biological and pharmaceutical applications. The presence of hydroxyl groups enhances its solubility in polar solvents and may influence its biological activity and stability. Additionally, the didehydro and tetrahydro modifications in its structure contribute to its unique spectral properties, which can be analyzed using UV-Vis spectroscopy. This compound may also play a role in plant physiology and could be involved in photoprotection mechanisms. Its potential applications span from food additives to nutraceuticals, highlighting its significance in both health and nutrition. Further research is necessary to fully elucidate its mechanisms of action and potential therapeutic benefits.

Formula: C₄₀H₅₆O₄

InChI: InChI=1/C40H56O4/c1-28(16-12-17-30(3)20-21-36-31(4)22-34(42)25-39(36,6)7)14-10-11-15-29(2)18-13-19-33(27-41)38(44)24-37-32(5)23-35(43)26-40(37,8)9/h10-22,34-36,41-43H,23-27H2,1-9H3/b11-10+,16-12+,18-13+,21-20+,28-14+,29-15+,30-17+,33-19+/t34-,35+,36-/m0/s1

Synonyms:

• .alpha.-Carotene-3,3',19-triol, 7,8-dihydro-8-oxo-
• .beta.,.epsilon.-Carotene-3,3',19-triol, 7,8-dihydro-8-oxo-
• (3R,3'R,6'R)-3,3',19-trihydroxy-4',5'-didehydro-5',6',7,8-tetrahydro-β,β-caroten-8-one

Siphonaxanthin

CAS: 28526-44-5

Siphonaxanthin is a naturally occurring carotenoid found primarily in green algae, specifically within the siphonaceous order. It exhibits a unique bioactive profile, primarily attributed to its structural properties, which allow for effective interaction with biological membranes. Siphonaxanthin functions by modulating key biological pathways, notably those involved in apoptosis and cell cycle regulation. This modulation is achieved through its antioxidant activity, which mitigates oxidative stress and influences signaling pathways integral to cellular health.

Formula: C₄₀H₅₆O₄

Purity: Min. 95%

Molecular weight: 600.87 g/mol

Ref: 3D-XS177355

Siphonaxanthin

CAS: 28526-44-5

Siphonaxanthin is a carotenoid found in green algae, known for targeting the death receptor 5 (DR5) on cancer cells to induce apoptosis. In human leukemia HL-60 cells, it increases DR5 expression, reduces Bcl-2 levels, and activates caspase-3. It also inhibits fibroblast growth factor receptor-1 (FGFR-1) signaling in endothelial cells. Siphonaxanthin suppresses the proliferation, migration, and tubular formation of human umbilical vein endothelial cells (HUVECs), as well as the growth of microvessels in rat aorta rings. Additionally, it has anti-inflammatory properties by blocking the translocation of high-affinity IgE receptors (FcεRI) to lipid rafts in mast cells. Siphonaxanthin shows potential for research into diseases such as cancer, diabetic retinopathy, and rheumatoid arthritis.

Formula: C₄₀H₅₆O₄

Color and Shape: Solid

Molecular weight: 600.87

Ref: TM-TN9850

Siphonaxanthin

CAS: 28526-44-5

Formula: C₄₀H₅₆O₄

Molecular weight: 600.88

Ref: 4Z-S-228001