CAS 2854-40-2

Pyrrolo[1,2-a]pyrazine-1,4-dione,hexahydro-3-(1-methylethyl)-, (3S,8aS)-

Description:

Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1-methylethyl)-, (3S,8aS)-, commonly referred to by its CAS number 2854-40-2, is a heterocyclic organic compound characterized by its unique bicyclic structure that includes both a pyrrole and a pyrazine moiety. This compound features a hexahydro framework, indicating the presence of a saturated ring system, and a substituent group that includes an isopropyl group, contributing to its overall stability and reactivity. The stereochemistry of the compound is defined by the (3S,8aS) configuration, which influences its biological activity and interaction with other molecules. Pyrrolo[1,2-a]pyrazine derivatives are of interest in medicinal chemistry due to their potential pharmacological properties, including antimicrobial and anticancer activities. The compound's solubility, melting point, and other physical properties can vary based on its specific formulation and purity. Overall, this substance represents a class of compounds that may have significant applications in drug development and synthetic chemistry.

Formula: C₁₀H₁₆N₂O₂

Synonyms:

• Pyrrolo[1,2-a]pyrazine-1,4-dione,hexahydro-3-(1-methylethyl)-, (3S-trans)-
• Pyrrolo[1,2-a]pyrazine-1,4-dione,hexahydro-3-isopropyl-, (S,S)- (8CI)
• (-)-(6S,9S)-Cyclo(prolylvalyl)
• Cyclo(L-Pro-L-Val)
• Cyclo(L-Val-L-Pro)
• Cyclo(L-prolyl-L-valine)
• Cyclo(L-prolyl-L-valyl)
• L-Valyl-L-prolyl lactam
• Maculosin 5
• cyclo(Pro-Val)
• (3S,8aS)-3β-Isopropyl-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione
• (3S,8aS)-3-propan-2-yl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
• (3S,8aα)-3β-Isopropyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione
• (3S,8aS)-3-Isopropyl-6,7,8,8aα-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione
• Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1-methylethyl)-, (3S,8aS)-
• (3S,8aS)-3-(propan-2-yl)-octahydropyrrolo[1,2-a]p
• (3S,8aS)-Octahydro-3-(1-methylethyl)pyrrolo[1,2-a]pyrazine-1,4-dione

Cyclo(-Pro-Val)

CAS: 2854-40-2

Cyclo(Pro-Val) and other Pro-containing diketopiperazines were detected in roasted coffee. The amount of these compounds increases with the intensity of roasting, they contribute to the bitterness of taste. The bitter-tasting cyclodipeptide has also been detected in other foodstuffs as cocoa, chocolate, beef, and cheese. Cyclo(Pro-Val), which shows antifungal activity, has also been isolated from microorganisms and further natural sources.

Formula: C₁₀H₁₆N₂O₂

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 196.25

Ref: 01-4029472

PYRROLO[1,2-A]PYRAZINE-1,4-DIONE, HEXAHYDRO-3-(1-METHYLETHYL)-, (3S,8AS)-

CAS: 2854-40-2

Formula: C₁₀H₁₆N₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 196.2462

Ref: IN-DA002VNW

Cyclo(L-Pro-L-Val)

CAS: 2854-40-2

Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and COX-2 activation.

Formula: C₁₀H₁₆N₂O₂

Purity: 98.18%

Color and Shape: Solid

Molecular weight: 196.25

Ref: TM-T125120

Cyclo(L-Pro-L-Val)

CAS: 2854-40-2

Cyclo(L-Pro-L-Val)

Purity: ≥98%

Molecular weight: 196.25g/mol

Ref: 54-BUP11329

Cyclo(L-Pro-L-Val)

CAS: 2854-40-2

Formula: C₁₀H₁₆N₂O₂

Purity: >95.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 196.25

Ref: 3B-C3893

Cyclo(L-prolyl-L-valyl)-d8

CAS: 2854-40-2

Formula: C₁₀H₈D₈N₂O₂

Molecular weight: 204.30

Ref: 4Z-N-0676

Cyclo(L-prolyl-L-valyl)

CAS: 2854-40-2

Formula: C₁₀H₁₆N₂O₂

Molecular weight: 196.25

Ref: 4Z-N-0671

Cyclo(L-prolyl-L-valyl)

Controlled Product

CAS: 2854-40-2

Applications Cyclo(L-prolyl-L-valyl) is a metabolite found in various marine fungi and bacteria. It is a diketopiperazine derivative isolated from Bacillus thuringiensis and Bacillus endophyticus.
References Bell, R., et al.: J. Nat. Prod., 57, 1587 (1994); Park, Y., et al.: J. Nat. Prod., 69, 580 (2006); Tezuka, Y., et al.: Chem. Pharm. Bull., 42, 2612 (1994); Sansinenea, E., et al.: Tetrahedron Lett., 57, 2604 (2016);

Formula: C₁₀H₁₆N₂O₂

Color and Shape: Neat

Molecular weight: 196.25

Ref: TR-C989825

Cyclo(-Pro-Val)

CAS: 2854-40-2

Cyclo(-Pro-Val) is a type of natural product that has been shown to inhibit the growth of tumor cells. Cyclo(-Pro-Val) is a metabolite produced by the fungus Cryptococcus neoformans and may serve as a potential anti-cancer drug. The compound blocks mitochondrial membrane potential, which prevents cancer cells from multiplying. Cyclo(-Pro-Val) has also been shown to inhibit the growth of bacteria such as Pseudomonas aeruginosa and Burkholderia cepacia complex, although it has little or no effect on other types of bacteria and fungi.

Formula: C₁₀H₁₆N₂O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 196.25 g/mol

Ref: 3D-FC108325

Cyclo(L-Pro-L-Val)

CAS: 2854-40-2

Purity: 98%

Molecular weight: 196.25

Ref: 10-F951457