CAS 28540-82-1

tentoxin from alternaria tenuis

Description:

Tentoxin is a mycotoxin produced by the fungus Alternaria tenuis, which is known for its phytotoxic properties. This compound is characterized by its ability to inhibit photosynthesis in plants, leading to chlorosis and necrosis, which can significantly affect plant health and crop yields. Tentoxin is a cyclic peptide, and its structure includes a unique arrangement of amino acids that contributes to its biological activity. It is soluble in organic solvents, which facilitates its interaction with cellular membranes and biological systems. The compound has garnered attention in both agricultural and toxicological research due to its potential impact on food safety and plant pathology. Additionally, tentoxin's mode of action involves interference with the electron transport chain in chloroplasts, making it a subject of interest for studies on plant defense mechanisms and the ecological implications of fungal toxins. As with many mycotoxins, safety precautions are necessary when handling tentoxin due to its potential toxicity to humans and animals.

Formula: C₂₂H₃₀N₄O₄

InChI: InChI=1/C22H30N4O4/c1-14(2)11-17-22(30)26(5)18(12-16-9-7-6-8-10-16)21(29)23-13-19(27)25(4)15(3)20(28)24-17/h6-10,12,14-15,17H,11,13H2,1-5H3,(H,23,29)(H,24,28)/b18-12-/t15-,17-/m0/s1

SMILES: CC(C)C[C@H]1C(=O)N(C)/C(=C\c2ccccc2)/C(=NCC(=O)N(C)[C@@H](C)C(=N1)O)O

Synonyms:

• Tentoxin
• Ccris 8423
• Cycloleucyl-N-methylalanylglycyl-N-methyl dehydrophenylalanine
• Cyclo(N-methyl-L-alanyl-L-leucyl-alpha,beta-didehydro-N-methylphenylalanylglycyl), (Z)-
• (3S,6S,12Z)-1,6,7-trimethyl-3-(2-methylpropyl)-12-(phenylmethylidene)-1,4,7,10-tetraazacyclododecane-2,5,8,11-tetrone

Cyclo[N-methyl-L-alanyl-L-leucyl-(αZ)-α,β-didehydro-N-methylphenylalanylglycyl]

CAS: 28540-82-1

Formula: C₂₂H₃₀N₄O₄

Purity: ≥98%(HPLC)

Color and Shape: Solid

Molecular weight: 414.4980

Ref: IN-DA002VOH

Tentoxin from Alternaria tenuis

CAS: 28540-82-1

Tentoxin from Alternaria tenuis

Formula: C₂₂H₃₀N₄O₄

Purity: By hplc: 99.78% (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 414.50g/mol

Ref: 54-BIT1002

Tentoxin

CAS: 28540-82-1

Tentoxin, a cyclic peptide from fungi, shuts down F1 motor in plants at low doses; high doses exceed enzyme's function.

Formula: C₂₂H₃₀N₄O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 414.5

Ref: TM-T13123

Tentoxin

CAS: 28540-82-1

Formula: C₂₂H₃₀N₄O₄

Color and Shape: Neat

Molecular weight: 414.50

Ref: 04-C17236000

Tentoxin

CAS: 28540-82-1

Formula: C₂₂H₃₀N₄O₄

Color and Shape: Neat

Molecular weight: 414.5

Ref: TR-T019505

Tentoxin-d3

Controlled Product

CAS: 28540-82-1

Formula: C₂₂H₂₇D₃N₄O₄

Color and Shape: Off White Solid

Molecular weight: 417.52

Ref: TR-T019507

Tentoxin

CAS: 28540-82-1

Tentoxin is a plant extract that belongs to the Alternaria genus. It is extracted from the leaves of the plant, and it has been shown to have anti-inflammatory effects in vitro. Tentoxin has been shown to inhibit cyclooxygenase-2 (COX-2), leukotriene B4 (LTB4), and thromboxane A2 (TXA2) production by rat liver microsomes. The mechanism of action for these effects is not known, but may be due to its ability to bind with COX-1 or COX-2 proteins in a competitive manner and block their enzymatic activity. Tentoxin also contains a cyclic peptide that inhibits α subunit of protein phosphatase 2A, which may contribute to its anti-inflammatory activities.

Formula: C₂₂H₃₀N₄O₄

Purity: Min. 95%

Molecular weight: 414.5 g/mol

Ref: 3D-DBA54082