CAS 2857982-34-2

1-Pentyn-3-ol, 1-(2-amino-5,6,7,8-tetrahydropyrimido[4′,5′:3,4]cyclohept[1,2-b]indol-11-yl)-3-methyl-

Formula: C₂₁H₂₂N₄O

Synonyms:

• 1-Pentyn-3-ol, 1-(2-amino-5,6,7,8-tetrahydropyrimido[4′,5′:3,4]cyclohept[1,2-b]indol-11-yl)-3-methyl-

TTBK1/2-IN-3

CAS: 2857982-34-2

TTBK1/2-IN-3 (compound 10) is a potent inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, with IC50 values of 579 nM and 258 nM, respectively. TTBK1/2-IN-3 can reduce the expression of primary cilia on the surface of human induced pluripotent stem cells (iPSC).

Formula: C₂₁H₂₂N₄O

Color and Shape: Solid

Molecular weight: 346.426

Ref: TM-T206217