CAS 28585-51-5

1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Description:

1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, with CAS number 28585-51-5, is a nucleoside analog that exhibits structural features characteristic of both nucleosides and pyrimidine derivatives. This compound contains a deoxyribose sugar moiety, which is essential for its potential biological activity, particularly in the context of antiviral or anticancer research. The thioxo group and the dihydropyrimidinone structure contribute to its reactivity and may influence its interaction with biological targets, such as enzymes involved in nucleic acid synthesis. The presence of the methyl group at the 5-position of the pyrimidine ring can affect the compound's lipophilicity and overall pharmacokinetic properties. This compound's unique structure allows it to potentially mimic natural nucleosides, making it a candidate for further investigation in medicinal chemistry. Its characteristics, including solubility, stability, and biological activity, would be critical for evaluating its therapeutic potential.

Formula: C₁₀H₁₄N₂O₄S

InChI: InChI=1/C10H14N2O4S/c1-5-3-12(10(17)11-9(5)15)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1

Synonyms:

• 2-Thiothymidine

Thymidine, 2-thio-

CAS: 28585-51-5

Formula: C₁₀H₁₄N₂O₄S

Purity: 97%

Molecular weight: 258.2942

Ref: IN-DA002VQY

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

CAS: 28585-51-5

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Purity: 97%

Molecular weight: 258.3g/mol

Ref: 54-OR1074254

2-Thiothymidine

CAS: 28585-51-5

Formula: C₁₀H₁₄N₂O₄S

Purity: ≥ 95.0%

Color and Shape: White to off-white powder

Molecular weight: 258.3

Ref: 7W-GN6765

2-Thiothymidine

CAS: 28585-51-5

2-Thiothymidine is a Nucleoside Derivative - Thio-nucleoside.

Formula: C₁₀H₁₄N₂O₄S

Color and Shape: Solid

Molecular weight: 258.29

Ref: TM-TNU1567

2-Thiothymidine

CAS: 28585-51-5

2-Thiothymidine is a hydrogen bond donor and acceptor that can be used as a substitute for thymine in the synthesis of DNA. 2-Thiothymidine has been shown to have successful in vivo treatment against bladder cancer and skin cells, as well as photochemical properties. It has been shown to inhibit the growth of prostate cancer cells by inhibiting DNA synthesis. 2-Thiothymidine binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming.
2-Thiothymidine is a nucleoside analog that is substituted for thymine during DNA synthesis. It inhibits the growth of prostate cancer cells by inhibiting DNA synthesis. It binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming.

Formula: C₁₀H₁₄N₂O₄S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 258.3 g/mol

Ref: 3D-NT02914

2-Thiothymidine

Controlled Product

CAS: 28585-51-5

Formula: C₁₀H₁₄N₂O₄S

Color and Shape: Neat

Molecular weight: 258.294

Ref: TR-T375288