FABP4/5-IN-4, identified by its CAS number 2862795-48-8, is a small molecule inhibitor that targets fatty acid-binding proteins (FABPs), specifically FABP4 and FABP5. These proteins play crucial roles in lipid metabolism and are implicated in various metabolic disorders, including obesity and diabetes. The compound is characterized by its ability to modulate the activity of these FABPs, potentially influencing cellular processes such as fatty acid transport and storage. In preclinical studies, FABP4/5-IN-4 has shown promise in reducing inflammation and improving metabolic profiles, making it a candidate for therapeutic applications in metabolic diseases. Its chemical structure typically includes functional groups that enhance its binding affinity to the target proteins, although specific structural details are proprietary. As research continues, the pharmacokinetics, efficacy, and safety profile of FABP4/5-IN-4 will be further elucidated, contributing to its potential development as a therapeutic agent.

FABP4/5-IN-4

2862795-48-8: FABP4/5-IN-4, identified by its CAS number 2862795-48-8, is a small molecule inhibitor that targets fatty acid-binding proteins (FABPs), specifically FABP4 and FABP5. These proteins play crucial roles in lipid metabolism and are implicated in various metabolic disorders, including obesity and diabetes. The compound is characterized by its ability to modulate the activity of these FABPs, potentially influencing cellular processes such as fatty acid transport and storage. In preclinical studies, FABP4/5-IN-4 has shown promise in reducing inflammation and improving metabolic profiles, making it a candidate for therapeutic applications in metabolic diseases. Its chemical structure typically includes functional groups that enhance its binding affinity to the target proteins, although specific structural details are proprietary. As research continues, the pharmacokinetics, efficacy, and safety profile of FABP4/5-IN-4 will be further elucidated, contributing to its potential development as a therapeutic agent.

FABP4/5-IN-4 (compound E1) effectively inhibits FABP 4 and FABP 5, displaying IC50 values of 3.78 μM and 5.72 μM, respectively. It is significant in the management of metabolic disorders such as diabetes mellitus [1].

CAS 2862795-48-8

FABP4/5-IN-4

FABP4/5-IN-4

Ref: TM-T86398