CAS 286370-15-8

N-[2-Chloro-4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl]-N'-propylurea

Description:

N-[2-Chloro-4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl]-N'-propylurea, with the CAS number 286370-15-8, is a chemical compound that belongs to the class of ureas. It features a complex structure characterized by a phenyl ring substituted with a chlorine atom and a quinazoline derivative that contains methoxy groups. This compound exhibits potential biological activity, often investigated for its role in medicinal chemistry, particularly in the development of pharmaceuticals. The presence of the quinazoline moiety suggests possible interactions with biological targets, making it of interest in drug discovery. Its solubility, stability, and reactivity can vary based on environmental conditions and the presence of other chemical entities. As with many organic compounds, safety and handling precautions are essential, as it may pose health risks if not managed properly. Overall, this compound exemplifies the intricate design often found in synthetic organic chemistry aimed at creating effective therapeutic agents.

Formula: C₂₀H₂₁ClN₄O₄

Synonyms:

• Krn-633
• 1-(2-Chloro-4-(6,7-Dimethoxyquinazolin-4-Yloxy)Phenyl)-3-Propylurea
• Krn633

1-{2-Chloro-4-[(6,7-dimethoxyquinazolin-4-yl)oxy]phenyl}-3-propylurea

CAS: 286370-15-8

Formula: C₂₀H₂₁ClN₄O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 416.8581

Ref: IN-DA002VX0

1-(2-Chloro-4-((6,7-Dimethoxyquinazolin-4-Yl)Oxy)Phenyl)-3-Propylurea

CAS: 286370-15-8

1-(2-Chloro-4-((6,7-Dimethoxyquinazolin-4-Yl)Oxy)Phenyl)-3-Propylurea

Purity: 98%

Molecular weight: 416.86g/mol

Ref: 54-OR1023198

KRN-633

CAS: 286370-15-8

KRN-633

Purity: ≥98%

Molecular weight: 416.86g/mol

Ref: 54-BUP13047

KRN 633

CAS: 286370-15-8

Formula: C₂₀H₂₁ClN₄O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystaline

Molecular weight: 416.86

Ref: 3B-K0063

KRN-633

CAS: 286370-15-8

KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.

Formula: C₂₀H₂₁ClN₄O₄

Purity: 99.53% - 99.73%

Color and Shape: Solid

Molecular weight: 416.86

Ref: TM-T6137