CAS 287096-87-1

(2R)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-amino-5-guanidino-pentanoyl]amino]hexanoyl]amino]hexanoyl]amino]-N-[(1R)-1-[[(1R)-1-[[(1R)-1-[[(1R)-1-[[2-[[(1R)-2-amino-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]amino]-2-oxo-ethyl]carbamoyl]pentyl]carbamoyl]pentyl]carbamo

Description:

The chemical substance with the name provided is a complex peptide, characterized by a long chain of amino acids linked by peptide bonds. Its structure indicates multiple functional groups, including amino and guanidino groups, which suggest it may have significant biological activity, potentially as a peptide hormone or a therapeutic agent. The presence of various amino acid residues implies that it could interact with biological receptors or enzymes, influencing physiological processes. The specific stereochemistry, indicated by the (R) configurations, suggests that the molecule may exhibit chiral properties, which can affect its biological interactions and pharmacokinetics. Additionally, the presence of a hydroxyphenyl group indicates potential for hydrogen bonding and hydrophobic interactions, which could enhance its stability and solubility in biological systems. Overall, this substance is likely to be of interest in medicinal chemistry and biochemistry due to its intricate structure and potential biological functions.

Formula: C₅₉H₁₀₅N₁₇O₁₁

InChI: InChI=1/C59H105N17O11/c1-7-13-22-40(51(81)68-36-48(78)69-47(49(61)79)35-37-29-31-38(77)32-30-37)71-53(83)42(24-15-9-3)73-55(85)44(26-17-11-5)75-57(87)46(28-20-34-67-59(64)65)76-56(86)45(27-18-12-6)74-54(84)43(25-16-10-4)72-52(82)41(23-14-8-2)70-50(80)39(60)21-19-33-66-58(62)63/h29-32,39-47,77H,7-28,33-36,60H2,1-6H3,(H2,61,79)(H,68,81)(H,69,78)(H,70,80)(H,71,83)(H,72,82)(H,73,85)(H,74,84)(H,75,87)(H,76,86)(H4,62,63,66)(H4,64,65,67)/t39-,40-,41-,42-,43-,44-,45-,46-,47-/m1/s1

Synonyms:

• RDP-1258
• RDP1258
• RDP-5
• Allotrap-1258
• Delmitide
• (2R)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pen tanoyl]amino]hexanoyl]amino]hexanoyl]amino]-N-[(1R)-1-[[(1R)-1-[[(1R)- 1-[[(1R)-1-[[(1R)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoylmethyl carbamoyl]pentyl]carbamoyl]pentyl]carbamoyl]pentyl]carbamoyl]-4-(diami nomethylideneamino)butyl]hexanamide
• Rationally Designed Peptide-58
• (2R)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-aMino-5-(diaMinoMethylideneaMino)pen tanoyl]aMino]hexanoyl]aMino]hexanoyl]aMino]-N-[(1R)-1-[[(1R)-1-[[(1R)- 1-[[(1R)-1-[[(1R)-1-carbaMoyl-2-(4-hydroxyphenyl)ethyl]carbaMoylMethyl carbaMoyl]pentyl]carbaMoyl]pentyl]carbaMoy
• RDP5
• D-Tyrosinamide, D-arginyl-D-norleucyl-D-norleucyl-D-norleucyl-D-arginyl-D-norleucyl-D-norleucyl-D-norleucylglycyl-

Delmitide

CAS: 287096-87-1

Delmitide, a TNF-alpha production inhibitor, is used potentially for the treatment of Crohn's disease and ulcerative colitis.

Formula: C₅₉H₁₀₅N₁₇O₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 1228.57

Ref: TM-T27142