CAS 287204-45-9

Pyrido[2,3-d]pyrimidin-7(8H)-one,6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-

Description:

Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl- is a complex organic compound characterized by its bicyclic structure, which incorporates both pyridine and pyrimidine rings. This compound features multiple functional groups, including a dichlorophenyl moiety and a fluoro-substituted methylphenyl group, contributing to its potential biological activity. The presence of halogen atoms, such as chlorine and fluorine, often enhances the lipophilicity and metabolic stability of the molecule, making it of interest in medicinal chemistry. The compound's structure suggests potential applications in pharmaceuticals, particularly in the development of targeted therapies. Its specific interactions with biological targets would depend on the arrangement of substituents and the overall three-dimensional conformation. Additionally, the compound's solubility, stability, and reactivity would be influenced by its functional groups and the electronic effects imparted by the halogens. Overall, this compound exemplifies the complexity and diversity of modern organic synthesis in drug discovery.

Formula: C₂₁H₁₅Cl₂FN₄O

Synonyms:

• Pd180970

PD180970

CAS: 287204-45-9

PD180970

Purity: ≥98%

Molecular weight: 429.27g/mol

Ref: 54-BUP10468

PD-180970

CAS: 287204-45-9

Formula: C₂₁H₁₅Cl₂FN₄O

Molecular weight: 429.27

Ref: 7W-GL5861

PD180970

CAS: 287204-45-9

PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.

Formula: C₂₁H₁₅Cl₂FN₄O

Purity: 98.67%

Color and Shape: Solid

Molecular weight: 429.27

Ref: TM-T23128