CYP1B1-IN-3, with the CAS number 2872575-51-2, is a chemical compound that serves as an inhibitor of the cytochrome P450 1B1 enzyme. This enzyme is involved in the metabolism of various endogenous and exogenous compounds, including certain drugs and environmental toxins. The inhibition of CYP1B1 has potential therapeutic implications, particularly in cancer treatment, as it may affect the bioactivation of procarcinogens and influence tumor progression. The compound is characterized by its specific binding affinity to the active site of the enzyme, which can lead to alterations in metabolic pathways. Additionally, CYP1B1-IN-3 may exhibit properties such as solubility in organic solvents and stability under physiological conditions, making it suitable for in vitro and in vivo studies. Its pharmacokinetic profile, including absorption, distribution, metabolism, and excretion (ADME) characteristics, is crucial for understanding its potential efficacy and safety in therapeutic applications. Further research is necessary to elucidate its full biological effects and potential clinical uses.

CYP1B1-IN-3

2872575-51-2: CYP1B1-IN-3, with the CAS number 2872575-51-2, is a chemical compound that serves as an inhibitor of the cytochrome P450 1B1 enzyme. This enzyme is involved in the metabolism of various endogenous and exogenous compounds, including certain drugs and environmental toxins. The inhibition of CYP1B1 has potential therapeutic implications, particularly in cancer treatment, as it may affect the bioactivation of procarcinogens and influence tumor progression. The compound is characterized by its specific binding affinity to the active site of the enzyme, which can lead to alterations in metabolic pathways. Additionally, CYP1B1-IN-3 may exhibit properties such as solubility in organic solvents and stability under physiological conditions, making it suitable for in vitro and in vivo studies. Its pharmacokinetic profile, including absorption, distribution, metabolism, and excretion (ADME) characteristics, is crucial for understanding its potential efficacy and safety in therapeutic applications. Further research is necessary to elucidate its full biological effects and potential clinical uses.

CYP1B1-IN-3: strong CYP1B1 inhibitor (IC50: 6.6 nM); weak on CYP1A1/CYP1A2; hinders cell migration, invasion; blocks P-gp, AKT/ERK, FAK/SRC, EMT.

CAS 2872575-51-2

CYP1B1-IN-3

CYP1B1-IN-3

Ref: TM-T73039