CAS 2873-36-1
:L-Leucyl-L-proline lactam
Description:
L-Leucyl-L-proline lactam, with the CAS number 2873-36-1, is a cyclic dipeptide derivative formed from the amino acids leucine and proline. This compound exhibits characteristics typical of peptides, including the presence of an amide bond and a lactam structure, which contributes to its stability and unique chemical properties. The lactam formation results in a cyclic structure that can influence its biological activity and solubility. L-Leucyl-L-proline lactam is often studied for its potential applications in pharmaceuticals and biochemistry, particularly in the context of peptide synthesis and drug design. Its structural features may impart specific interactions with biological targets, making it of interest in medicinal chemistry. Additionally, the presence of the branched-chain amino acid leucine may enhance its hydrophobic characteristics, while proline's unique cyclic structure can introduce conformational rigidity. Overall, this compound exemplifies the complexity and functionality of peptide derivatives in chemical and biological systems.
Formula:C11H18N2O2
InChI:InChI=1/C11H18N2O2/c1-7(2)6-8-11(15)13-5-3-4-9(13)10(14)12-8/h7-9H,3-6H2,1-2H3,(H,12,14)/t8-,9-/m0/s1
InChI key:InChIKey=SZJNCZMRZAUNQT-IUCAKERBSA-N
SMILES:O=C1N2[C@](C(=O)N[C@H]1CC(C)C)(CCC2)[H]
Synonyms:- (3S,8aS)-3-(2-methylpropyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
- (3S,8aS)-Hexahydro-3-(2-methylpropyl)pyrrolo[1,2-a]pyrazine-1,4-dione
- 3-(2-Methylpropyl)Hexahydropyrrolo[1,2-A]Pyrazine-1,4-Dione
- <span class="text-smallcaps">L</smallcap>-Leucyl-<smallcap>L</span>-proline lactam
- <span class="text-smallcaps">L</smallcap>-Leucyl-<smallcap>L</span>-prolyl lactam
- Brn 0085716
- Cyclo(-Leu-Pro)
- Cyclo(<span class="text-smallcaps">L</smallcap>-Leu-<smallcap>L</span>-Pro)
- Cyclo(<span class="text-smallcaps">L</smallcap>-Pro-<smallcap>L</span>-Leu)
- Cyclo(<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</span>-prolyl)
- Cyclo(<span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</span>-leucyl)
- Cyclo(Pro-Leu)
- Cyclo(proline-leucine)
- Cyclo-<span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</span>-leucine
- Cyclo-L-leu-L-pro
- Gancidin W
- Maculosin 6
- Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl)-, (3S-trans)-
- Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-3-isobutyl-, stereoisomer
- Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl)-, (3S,8aS)-
- cis-Cyclo(<span class="text-smallcaps">L</smallcap>-Leu-<smallcap>L</span>-Pro)
- L-Leucyl-L-proline lactam
- (3S-trans)-Hexahydro-3-isobutylpyrrolo(1,2-a)pyrazine-1,4-dione
- 5-24-07-00347 (Beilstein Handbook Reference)
- Cyclo-L-prolyl-L-leucine
- Cyclo(-L-Leu-L-Pro)≥ 99% (TLC)
- gancidinw
- 3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
- (3S,8aS)-2,3,6,7,8,8a-Hexahydro-3-(2-methylpropyl)pyrrolo[1,2-a]pyrazine-1,4-dione
- (3S,8aS)-3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
- 3-isobutyl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-quinone
- (3S,8aS)-Octahydro-3-(2-methylpropyl)pyrrolo[1,2-a]pyrazine-1,4-dione
- Cyclo(L-prolyl-L-leucyl)
- L-Leucyl-L-prolyl lactaM
- 3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
- Cyclo(L-Pro-L-Leu-)
- Cyclo(L-leucyl-L-prolyl-)
- 4-dione,hexahydro-3-(2-methylpropyl)-2-a)pyrazine-(3s-trans)-pyrrolo(
- Cyclo(L-Pro-D-Leu)
- (3S-trans)-Hexahydro-3-(2-Methylpropyl)-pyrrolo[1,2-a]pyrazine-1,4-dione
- See more synonyms
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Found 12 products.
Cyclo(-Leu-Pro)
CAS:Cyclo(Leu-Pro) showed antibacterial activity. Yan et al. observed that Cyclo(Leu-Pro) produced by Achromobacter xylosoxidans inhibited aflatoxin production by Aspergillus parasiticus. The diketopiperazine was shown to inhibit catecholamine release in vitro. It could play a role in the hypothalamic modulation of appetite suppressant circuitry.Formula:C11H18N2O2Purity:> 99%Color and Shape:White PowderMolecular weight:210.28Cyclo(L-Leu-L-Pro)
CAS:Cyclo(L-Leu-L-Pro) is a compound from Pseudomonas sesquiterpenes BC42 with antifungal activity that inhibits fungal pathogens.Formula:C11H18N2O2Purity:>99.99%Color and Shape:SolidMolecular weight:210.27Cyclo(L-Pro-L-Leu)
CAS:Formula:C11H18N2O2Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:210.28Cyclo(L-prolyl-L-leucyl)
CAS:Controlled ProductApplications Sorbicillin analog. A bioactive secondary metabolites from terrestrial Streptomyces species TN262.
References Ma, L. et al. : J. Anitibiot. 64, 645 (2011); Elleuch, L. et al.: Appl. Biochem. Biotech. 162, 579 (2010)Formula:C11H18N2O2Color and Shape:NeatMolecular weight:210.27Cyclo(L-prolyl-L-leucyl)
CAS:Cyclo(L-prolyl-L-leucyl) is a cyclic lipopeptide that inhibits the transcription of DNA. It binds to the polymerase chain and blocks the transcription process, which prevents the production of RNA. Cyclo(L-prolyl-L-leucyl) has been shown to have an inhibitory effect on human pathogens such as fungi, protozoa, or bacteria. Cyclo(L-prolyl-L-leucyl) also has anti-cancer properties and is used for cancer treatment. Cyclo(L-prolyl-L-leucyl) is extracted from an acetate extract and purified by chromatography. The purified product is then tested in vitro using assays including magnetic resonance spectroscopy.
Formula:C11H18N2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:210.27 g/mol(3S,8aS)-3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
CAS:Formula:C11H18N2O2Purity:95%Color and Shape:SolidMolecular weight:210.277
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