CAS 287405-51-0

3-Thiomorpholinecarboxamide,N-hydroxy-4-[[4-[(4-hydroxy-2-butyn-1-yl)oxy]phenyl]sulfonyl]-2,2-dimethyl-,(3S)-

Description:

3-Thiomorpholinecarboxamide, N-hydroxy-4-[[4-[(4-hydroxy-2-butyn-1-yl)oxy]phenyl]sulfonyl]-2,2-dimethyl-, (3S)-, identified by CAS number 287405-51-0, is a synthetic organic compound characterized by its complex structure, which includes a thiomorpholine ring, a sulfonyl group, and a hydroxybutynyl moiety. This compound exhibits properties typical of amides and sulfonamides, including potential solubility in polar solvents and the ability to form hydrogen bonds due to the presence of hydroxyl and amide functional groups. Its stereochemistry, indicated by the (3S) designation, suggests specific spatial arrangements that may influence its biological activity and interactions with other molecules. The presence of the sulfonyl group often enhances the compound's reactivity and can contribute to its pharmacological properties. Overall, this compound may be of interest in medicinal chemistry, particularly in the development of therapeutic agents, due to its unique structural features and potential biological applications.

Formula: C₁₇H₂₂N₂O₆S₂

Synonyms:

• 3-Thiomorpholinecarboxamide,N-hydroxy-4-[[4-[(4-hydroxy-2-butynyl)oxy]phenyl]sulfonyl]-2,2-dimethyl-, (3S)-(9CI)
• Apratastat
• Tmi 005

Apratastat

CAS: 287405-51-0

Apratastat is a drug that inhibits the production of TNF-α, one of the cytokines responsible for inflammation and tissue damage. Apratastat has been shown to be effective in reducing lung damage caused by exposure to smoke or ozone. It also reduces the inflammatory response in skin diseases such as atopic dermatitis and psoriasis. This drug is administered orally and is excreted unchanged in urine. Apratastat has been shown to have biocompatible properties with a long half-life, which makes it suitable for specific treatment of conditions such as chronic obstructive pulmonary disease (COPD).

Formula: C₁₇H₂₂N₂O₆S₂

Purity: Min. 95%

Molecular weight: 414.5 g/mol

Ref: 3D-MLA40551

Apratastat

CAS: 287405-51-0

Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)

Formula: C₁₇H₂₂N₂O₆S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 414.5

Ref: TM-T14312