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CAS 2878473-51-7

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  • ATM Inhibitor-11
    Targetmol
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    ATM Inhibitor-11

    CAS:
    <p>ATMInhibitor-11 (Compound 1) is an inhibitor of ATM with an IC50 of 0.32 nM. It also inhibits KAP1 phosphorylation with an IC50 of 0.97 nM. This compound exhibits high exposure in the brain, heart, and plasma of ICR mice. Furthermore, ATMInhibitor-11 demonstrates antitumor activity in the NCI-H441 xenograft mouse model.</p>
    Formula:C27H33FN6O2
    Color and Shape:Solid
    Molecular weight:492.59

    Ref: TM-T201457