CAS 2881017-49-6

Cyclohexanone, 2-(4-fluorophenyl)-2-(methylamino)-, (2R)-

Description:

Cyclohexanone, 2-(4-fluorophenyl)-2-(methylamino)-, (2R)-, identified by CAS number 2881017-49-6, is a chemical compound characterized by its cyclohexanone backbone, which is a six-membered cyclic ketone. The presence of a 4-fluorophenyl group and a methylamino group at the second carbon position contributes to its unique properties. This compound is likely to exhibit moderate polarity due to the presence of the amino group, which can engage in hydrogen bonding. The fluorine atom in the phenyl ring may influence its electronic properties, potentially enhancing its reactivity or altering its interaction with biological targets. As a chiral molecule, it exists in two enantiomeric forms, with the (2R)- configuration being one of them, which may have implications for its biological activity and pharmacological effects. Cyclohexanone derivatives are often studied for their applications in organic synthesis and medicinal chemistry, making this compound of interest in various research fields. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity or reactivity.

Formula: C₁₃H₁₆FNO

Synonyms:

• Cyclohexanone, 2-(4-fluorophenyl)-2-(methylamino)-, (2R)-

Blixeprodil

CAS: 2881017-49-6

Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.

Formula: C₁₃H₁₆FNO

Color and Shape: Solid

Molecular weight: 221.271

Ref: TM-T206599