CAS 2882035-56-3
:PCSK9-IN-11
Description:
PCSK9-IN-11, identified by its CAS number 2882035-56-3, is a small molecule inhibitor targeting the proprotein convertase subtilisin/kexin type 9 (PCSK9) enzyme. This enzyme plays a crucial role in cholesterol metabolism by regulating the degradation of low-density lipoprotein (LDL) receptors in the liver. Inhibition of PCSK9 can lead to increased LDL receptor levels, thereby enhancing the clearance of LDL cholesterol from the bloodstream, which is beneficial in managing hypercholesterolemia and reducing cardiovascular risk. PCSK9-IN-11 is characterized by its specific binding affinity to the PCSK9 protein, which prevents it from interacting with LDL receptors. The compound is typically evaluated for its pharmacokinetic properties, efficacy in lowering cholesterol levels, and safety profile in preclinical and clinical studies. As a research compound, it contributes to the development of novel therapeutic strategies for lipid disorders and cardiovascular diseases. Further studies are essential to fully understand its mechanism of action and potential clinical applications.
Formula:C16H17ClFN5O3
Synonyms:- PCSK9-IN-11
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