CAS 288262-96-4

N-[5-Chloro-2-[2-[4-(4-fluorobenzyl)-2(R)-methylpiperazin-1-yl]-2-oxoethoxy]phenyl]urea hydrochloride

Description:

N-[5-Chloro-2-[2-[4-(4-fluorobenzyl)-2(R)-methylpiperazin-1-yl]-2-oxoethoxy]phenyl]urea hydrochloride, with CAS number 288262-96-4, is a chemical compound characterized by its complex structure, which includes a urea moiety and multiple aromatic and heterocyclic components. This substance typically exhibits properties such as solubility in polar solvents, which is common for compounds containing urea and piperazine groups. The presence of a chloro substituent and a fluorobenzyl group suggests potential biological activity, possibly as a pharmaceutical agent. The compound may interact with biological targets due to its ability to form hydrogen bonds and engage in π-π stacking interactions, which are significant in drug-receptor binding. Additionally, the hydrochloride form indicates that it is a salt, which can enhance its stability and solubility in aqueous environments. Overall, this compound's unique structural features contribute to its potential applications in medicinal chemistry and pharmacology.

Formula: C₂₁H₂₅Cl₂FN₄O₃

Synonyms:

• Zk-811752
• Bx-471

BX471 HCl

CAS: 288262-96-4

Formula: C₂₁H₂₅Cl₂FN₄O₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 471.3526

Ref: IN-DA00BF2N

(R)-1-(5-Chloro-2-(2-(4-(4-Fluorobenzyl)-2-Methylpiperazin-1-Yl)-2-Oxoethoxy)Phenyl)Urea Hydrochloride

CAS: 288262-96-4

(R)-1-(5-Chloro-2-(2-(4-(4-Fluorobenzyl)-2-Methylpiperazin-1-Yl)-2-Oxoethoxy)Phenyl)Urea Hydrochloride

Purity: 98%

Molecular weight: 471.35g/mol

Ref: 54-PC108433

BX471 hydrochloride

CAS: 288262-96-4

BX471 hydrochloride is a selective antagonist of the C-C chemokine receptor type 1 (CCR1), which is synthesized through rigorous chemical processes. It operates by inhibiting the binding of chemokines to the CCR1 receptor, thus interfering with the signaling pathways that lead to inflammation and immune responses. This mechanism is specifically effective in modulating immune system functions and controlling pathophysiological responses in various tissue types.

Formula: C₂₁H₂₅Cl₂FN₄O₃

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 471.35 g/mol

Ref: 3D-NLA26296

BX471 hydrochloride

CAS: 288262-96-4

BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.

Formula: C₂₁H₂₅Cl₂FN₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 471.35

Ref: TM-T14845