CAS 2884554-45-2

UBX-382

Formula: C₄₂H₄₄N₁₀O₄

Synonyms:

• UBX-382
• 1H-Isoindole-1,3(2H)-dione, 5-[4-[[7-[[3-[(2,6-dimethylphenyl)amino]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl]amino]-3,4-dihydro-2(1H)-isoquinolinyl]methyl]-1-piperidinyl]-2-(2,6-dioxo-3-piperidinyl)-

UBX-382

CAS: 2884554-45-2

UBX-382 is an orally administered proteolysis-targeting chimera (PROTAC) designed to target BTK and disrupt B-cell receptor signaling. It demonstrates enhanced degradation of both wild-type and mutant BTK proteins, exhibiting anti-cancer effects in murine xenograft models using TMD-8 cells [1].

Formula: C₄₂H₄₄N₁₀O₄

Molecular weight: 752.86

Ref: TM-T87590