CAS 28862-80-8

Z-D-Met-OH

Description:

Z-D-Met-OH, with the CAS number 28862-80-8, is a chemical compound that belongs to the class of amino acids and derivatives. It is characterized by the presence of a Z (benzyloxycarbonyl) protecting group on the amino group and a methionine (Met) side chain, which includes a sulfur atom. This compound is typically used in peptide synthesis and research applications due to its ability to protect the amino group during chemical reactions, allowing for selective modifications of other functional groups. Z-D-Met-OH is soluble in polar solvents, which facilitates its use in various biochemical assays and synthetic pathways. Its stability and reactivity make it a valuable intermediate in the production of more complex peptides and proteins. As with many chemical substances, proper handling and safety precautions should be observed, as it may have specific hazards associated with its use.

Formula: C₁₃H₁₇NO₄S

InChI: InChI=1/C13H17NO4S/c1-19-8-7-11(12(15)16)14-13(17)18-9-10-5-3-2-4-6-10/h2-6,11H,7-9H2,1H3,(H,14,17)(H,15,16)/t11-/m1/s1

InChI key: InChIKey=FPKHNNQXKZMOJJ-LLVKDONJSA-N

SMILES: C(OC(N[C@H](CCSC)C(O)=O)=O)C1=CC=CC=C1

Synonyms:

• (2R)-4-Methylsulfanyl-2-(phenylmethoxycarbonylamino)butanoic acid
• (R)-2-(Benzyloxycarbonylamino)-4-(methylthio)butanoic acid
• <span class="text-smallcaps">D</span>-(Carbobenzyloxy)methionine
• <span class="text-smallcaps">D</span>-Methionine, N-[(phenylmethoxy)carbonyl]-
• CBZ-<span class="text-smallcaps">D</span>-Methionine
• Cbz-D-methionine
• Methionine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">D</span>-
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">D</span>-methionine
• N-Benzyloxycarbonyl-D-methionine
• N-Carbobenzoxy-D-methionine
• N-Carbobenzyloxy-<span class="text-smallcaps">D</span>-methionine
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">D</span>-methionine
• z-D-Met
• D-(Carbobenzyloxy)methionine
• N-[(Phenylmethoxy)carbonyl]-D-methionine
• D-Methionine, N-[(phenylmethoxy)carbonyl]-
• Methionine, N-carboxy-, N-benzyl ester, D-
• Z-D-MET-OH
• N-CBZ-D-METHIONINE
• N-ALPHA-CARBOBENZOXY-D-METHIONINE
• Z-D-METHIONINE
• N-Cbz-D-Met-OH
• N-ALPHA-CBZ-D-METHIONINE
• Z-D-Met-OH
• N-Cbz-D-methionine
• CBZ-D-MET-OH
• Z-D-METHIONINE extrapure
• Z-D-methionine≥ 99% (HPLC)
• (R)-2-(Benzyloxycarbonylamino)-4-methylthiobutyric acid
• N-ALPHA-BENZYLOXYCARBONYL-D-METHIONINE
• Cbz-D-Methinine

N-Carbobenzoxy-D-methionine

CAS: 28862-80-8

Formula: C₁₃H₁₇NO₄S

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 283.34

Ref: 3B-C0665

N-Benzyloxycarbonyl-D-methionine, 98%

CAS: 28862-80-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₃H₁₇NO₄S

Purity: 98%

Molecular weight: 283.34

Ref: 02-H63152

D-Methionine, N-[(phenylmethoxy)carbonyl]-

CAS: 28862-80-8

Formula: C₁₃H₁₇NO₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 283.3434

Ref: IN-DA002WVK

N-Carbobenzoxy-D-Methionine

CAS: 28862-80-8

N-Carbobenzoxy-D-Methionine

Purity: 98%

Molecular weight: 283.34g/mol

Ref: 54-OR1014315

Z-D-Methionine extrapure, 99%

CAS: 28862-80-8

Formula: C₁₃H₁₇NO₄S

Purity: min. 99.0%

Color and Shape: White to off - white, Powder

Molecular weight: 283.40

Ref: SR-91642

(R)-2-(((Benzyloxy)carbonyl)amino)-4-(methylthio)butanoic acid

CAS: 28862-80-8

Formula: C₁₃H₁₇NO₄S

Purity: 95%

Color and Shape: Solid

Molecular weight: 283.34

Ref: 10-F239052

N-Cbz-D-methionine

Controlled Product

CAS: 28862-80-8

Applications N-Cbz-D-methionine is an N-Cbz-protected form of D-Methionine (M260550). D-Methionine is an isomer of L-Methionine (M260440), and is known to be a cytoprotectant against Cisplatin (C499500), an anticancer agent. D-Methionine is also used to prevent noise- and drug-induced hearing loss, as well as hair loss (all of which may also be caused by Cisplatin or aminoglycosides).
References Campbell, K., et al.: Hear. Res., 92, 103 (2007); Cloven, N., et al.: Antican. Res., 20.6B, 4205 (1999); Vuyyuri, S., et al.: Clin. Cancer Res., 14, 2161 (2008)

Formula: C₁₃H₁₇NO₄S

Color and Shape: Neat

Molecular weight: 283.34

Ref: TR-C227740