CAS 288628-05-7

6,7,8,9,10,11-Hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl sulfamate

Description:

6,7,8,9,10,11-Hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl sulfamate is a chemical compound characterized by its complex bicyclic structure, which includes a fused cycloheptane and a benzene ring. The presence of a sulfamate group indicates that it contains a sulfur atom bonded to an oxygen atom and a nitrogen atom, contributing to its potential reactivity and biological activity. This compound is likely to exhibit properties typical of sulfamates, such as being a potential inhibitor or modulator in various biochemical pathways. Its hexahydro structure suggests it is saturated, which may influence its solubility and stability in different solvents. The oxo group in the structure implies the presence of a carbonyl functionality, which can participate in various chemical reactions, including nucleophilic attacks. Overall, the unique structural features of this compound may confer specific pharmacological properties, making it of interest in medicinal chemistry and drug development. However, detailed studies would be necessary to fully elucidate its characteristics and potential applications.

Formula: C₁₄H₁₅NO₅S

InChI: InChI=1S/C14H15NO5S/c15-21(17,18)20-9-6-7-11-10-4-2-1-3-5-12(10)14(16)19-13(11)8-9/h6-8H,1-5H2,(H2,15,17,18)

InChI key: InChIKey=DSLPMJSGSBLWRE-UHFFFAOYSA-N

SMILES: O=C1C2=C(C=3C(=CC(OS(N)(=O)=O)=CC3)O1)CCCCC2

Synonyms:

• 6,7,8,9,10,11-Hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl sulfamate
• 667-Coumate
• Bn 83495
• Irosustat
• Stx 64
• Sulfamic acid, 6,7,8,9,10,11-hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl ester

Sulfamic acid, 6,7,8,9,10,11-hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl ester

CAS: 288628-05-7

Formula: C₁₄H₁₅NO₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 309.3376

Ref: IN-DA002WVW

Irosustat

CAS: 288628-05-7

Irosustat

Purity: ≥98%

Molecular weight: 309.34g/mol

Ref: 54-BUP10042

Irosustat

CAS: 288628-05-7

Irosustat (667-Coumate) is a potent steroid sulfatase inhibitor, with an IC50 of 8 nM, and exhibits anti-breast cancer activity.

Formula: C₁₄H₁₅NO₅S

Purity: 99.33%

Color and Shape: Solid

Molecular weight: 309.34

Ref: TM-T4464

STX64

Controlled Product

CAS: 288628-05-7

Formula: C₁₄H₁₅NO₅S

Color and Shape: Neat

Molecular weight: 309.34

Ref: TR-S687208

STX64

CAS: 288628-05-7

STX64 is an inhibitor of sulfatase, a class of enzymes that catalyzes the hydrolysis of sulfate esters. It has been shown to inhibit cancer cells in vitro and in vivo. STX64 also inhibits steroid sulfatase, which is an enzyme that catalyzes the conversion of steroids to inactive metabolites. This drug has a potential for use as a chemotherapeutic agent for breast cancer. STX64 binds to the active site of the enzyme and prevents other molecules from binding, thereby preventing the conversion process. STX64 may be used in combination with other drugs to prevent drug interactions by inhibiting their metabolism.

Formula: C₁₄H₁₅NO₅S

Purity: Min. 95%

Molecular weight: 309.34 g/mol

Ref: 3D-NLA62805