CAS 28888-44-0

6,7-Dimethoxy-2,4(1H,3H)-quinazolinedione

Description:

6,7-Dimethoxy-2,4(1H,3H)-quinazolinedione, with the CAS number 28888-44-0, is a synthetic organic compound belonging to the quinazoline family. This compound features a quinazoline core structure, which is characterized by a fused bicyclic system containing two nitrogen atoms. The presence of methoxy groups at the 6 and 7 positions enhances its solubility and may influence its biological activity. Typically, quinazolinediones exhibit a range of pharmacological properties, including potential anti-cancer and anti-inflammatory activities. The compound is likely to be a solid at room temperature and may have moderate stability under standard conditions. Its reactivity can be attributed to the presence of the carbonyl groups in the structure, which can participate in various chemical reactions. As with many organic compounds, safety precautions should be observed when handling it, as it may pose health risks if ingested or inhaled. Overall, 6,7-Dimethoxy-2,4(1H,3H)-quinazolinedione is of interest in medicinal chemistry and may serve as a lead compound for further drug development.

Formula: C₁₀H₁₀N₂O₄

InChI: InChI=1/C10H10N2O4/c1-15-7-3-5-6(4-8(7)16-2)11-10(14)12-9(5)13/h3-4H,1-2H3,(H2,11,12,13,14)

InChI key: InChIKey=KWNQIIMVPSMYEM-UHFFFAOYSA-N

SMILES: O=C1C=2C(=CC(OC)=C(OC)C2)NC(=O)N1

Synonyms:

• 1,2,3,4-TETRAHYDRO-6,7-Dimethoxyquinazoline-2,4-dione
• 2,4(1H,3H)-Quinazolinedione, 6,7-dimethoxy-
• 2,4-Dihydroxy-6,7-diMethoxyquinazoline
• 2,4-Dihydroxy-6,7-dimethoxquinazoline
• 2,4-dione-6,7-DIMETHOXYQUINAZOLINE
• 2,5-Dihydroxy-6,7-dimethoxyquinazoline
• 6,7-Dimethoxy-(1H,3H)-2,4-Quinazolindione
• 6,7-Dimethoxy-1H-quinazoline-2,4-dione
• 6,7-Dimethoxy-2,4-Quinazoline-Dione
• 6,7-Dimethoxy-2-4(1H,3H)-Quinazolinedione
• 6,7-Dimethoxyquinazolin-2,4(1H,3H)-dione
• 6,7-Dimethoxyquinazoline-2,4-diol
• 6,7-dimethoxy-2,4-(1H,3H)-Quinazolinedione
• 6,7-dimethoxyquinazoline-2,4(1H,3H)-dione
• Labotest-Bb Lt00453115
• 6,7-Dimethoxyquinazoline-2,4-dione
• 6,7-DIMETHOXY-2,4-QUINAZOLINEDIONE
• 6,7-Dimethoxyquinazoline-2,4-d
• 6,7-dimethoxquinazoline-2,4(1h,3h)-dione
• 6,7-Dimethoxy-2,4-(1H,3H)quinazolidion
• 6,7-DIMETHOXYQUINAZOLINE-2,4-DIONE 98%
• 6,7-DIMETHOXY-QUINAZOLINE-2,4-DIOL
• 6,7-[ DIMETHOXYQUINAZOLINE-2,4-DIONE [6,7-DIMETHOXY-2,4(1H,3H)QUINAZOLINEDIONETERAZOSIN
• 2,4-Dihydroxyl-6,7-dimethoxyquinazoline
• QUINAZOLINDIONE

6,7-Dimethoxyquinazoline-2,4-dione

CAS: 28888-44-0

Formula: C₁₀H₁₀N₂O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 222.20

Ref: 3B-D1839

DOXAZOSIN IMPURITY D CRS

CAS: 28888-44-0

DOXAZOSIN IMPURITY D CRS

Ref: 41-Y0000551

Doxazosin impurity standard

CAS: 23680-84-4, 28888-44-0, 60547-97-9, 77883-43-3

Doxazosin impurity standard

Color and Shape: Off White

Ref: 47-1301

Doxazosin Related Compound B (6,7-dimethoxyquinazoline-2,4-dione)

CAS: 28888-44-0

Aromatic or modified aromatic drugs with nitrogen hetero-atom(s) only, not elsewhere specified or included

Formula: C₁₀H₁₀N₂O₄

Color and Shape: White Powder

Molecular weight: 222.06406

Ref: 45-1225441

2,4(1H,3H)-Quinazolinedione, 6,7-dimethoxy-

CAS: 28888-44-0

Formula: C₁₀H₁₀N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 222.1974

Ref: IN-DA002WYC

6,7-Dimethoxyquinazoline-2,4-dione

CAS: 28888-44-0

6,7-Dimethoxyquinazoline-2,4-dione

Purity: 98%

Molecular weight: 222.20g/mol

Ref: 54-OR1011970

Doxazosin EP Impurity D (Doxazosin USP Related Compound B)

Controlled Product

CAS: 28888-44-0

Formula: C₁₀H₁₀N₂O₄

Color and Shape: Neat

Molecular weight: 222.20

Ref: 86-MM0085.07

Doxazosin Impurity 5

CAS: 28888-44-0

Formula: C₁₀H₁₀N₂O₄

Molecular weight: 222.20

Ref: 4Z-D-1416

Doxazosin EP Impurity D

CAS: 28888-44-0

Formula: C₁₀H₁₀N₂O₄

Molecular weight: 222.2

Ref: ST-EA-CP-D26004

6,7-Dimethoxyquinazoline-2,4-dione

Controlled Product

CAS: 28888-44-0

Impurity Doxazosin EP Impurity D
Applications 6,7-Dimethoxyquinazoline-2,4-dione (Doxazosin EP Impurity D) is an intermediate in the preparation of Alfuzosin hydrochloride (A532000), an antihypertensive.
References Khalifa, M., et al.: Pharmazie, 37, 115 (1982), Ion, A., et al.: Green Chem., 9, 158 (2007), Sakakura, T., et al.: Chem. Rev., 107, 2365 (2007),

Formula: C₁₀H₁₀N₂O₄

Color and Shape: White To Off-White

Molecular weight: 222.20

Ref: TR-D474950

6,7-Dimethoxyquinazoline-2,4-dione

CAS: 28888-44-0

6,7-Dimethoxyquinazoline-2,4-dione is a chemical compound that can be synthesized by reacting amide and formaldehyde. It has been investigated as an efficient method for the synthesis of amides. 6,7-Dimethoxyquinazoline-2,4-dione is also a potential antibacterial agent which may prevent bacterial growth by inhibiting choline uptake or by binding to ribosomes and blocking protein synthesis. The reaction mechanism of this compound is not well understood, but it may involve hydrolysis of cyanate to produce hydrogen cyanide (HCN), which then reacts with the amide to form the quinazoline ring.

Formula: C₁₀H₁₀N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 222.2 g/mol

Ref: 3D-FD22229

2,4-Dihydroxy-6,7-dimethoxyquinazoline

CAS: 28888-44-0

Formula: C₁₀H₁₀N₂O₄

Purity: 98%+(LC-MS);RG

Color and Shape: Solid, No data available.

Molecular weight: 222.2

Ref: 10-F024184

6,7-Dimethoxyquinazoline-2,4-dione, 98%

CAS: 28888-44-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Formula: C₁₀H₁₀N₂O₄

Purity: 98%

Color and Shape: Powder, White to pale cream

Molecular weight: 222.2

Ref: 02-L08411