PARP10/15-IN-3, identified by its CAS number 2892064-88-7, is a small molecule inhibitor that targets poly(ADP-ribose) polymerases (PARPs), specifically PARP10 and PARP15. These enzymes play crucial roles in cellular processes such as DNA repair, cell proliferation, and apoptosis. Inhibition of PARP10 and PARP15 can have significant implications in cancer therapy, particularly in tumors with deficiencies in DNA repair mechanisms. The compound is characterized by its ability to selectively inhibit these PARP isoforms, potentially leading to enhanced therapeutic efficacy in combination with other cancer treatments. Its chemical structure includes specific functional groups that contribute to its binding affinity and selectivity for the target enzymes. Research into PARP10/15-IN-3 is ongoing, focusing on its pharmacokinetics, bioavailability, and overall effectiveness in preclinical and clinical settings. As with many small molecule inhibitors, understanding its mechanism of action and potential side effects is crucial for its development as a therapeutic agent.

PARP10/15-IN-3

2892064-88-7: PARP10/15-IN-3, identified by its CAS number 2892064-88-7, is a small molecule inhibitor that targets poly(ADP-ribose) polymerases (PARPs), specifically PARP10 and PARP15. These enzymes play crucial roles in cellular processes such as DNA repair, cell proliferation, and apoptosis. Inhibition of PARP10 and PARP15 can have significant implications in cancer therapy, particularly in tumors with deficiencies in DNA repair mechanisms. The compound is characterized by its ability to selectively inhibit these PARP isoforms, potentially leading to enhanced therapeutic efficacy in combination with other cancer treatments. Its chemical structure includes specific functional groups that contribute to its binding affinity and selectivity for the target enzymes. Research into PARP10/15-IN-3 is ongoing, focusing on its pharmacokinetics, bioavailability, and overall effectiveness in preclinical and clinical settings. As with many small molecule inhibitors, understanding its mechanism of action and potential side effects is crucial for its development as a therapeutic agent.

CAS 2892064-88-7

PARP10/15-IN-3

PARP10/15-IN-3

Ref: 54-OR1063595