CAS 2893809-51-1

Benzo[b]thiophene-3-carbonitrile, 2-amino-4-[4-[(2S,5R)-2,5-dimethyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]-6-(trifluoromethyl)-7-quinazolinyl]-7-fluoro-, (4S)-

Description:

Benzo[b]thiophene-3-carbonitrile, 2-amino-4-[4-[(2S,5R)-2,5-dimethyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]-6-(trifluoromethyl)-7-quinazolinyl]-7-fluoro-, (4S)- is a complex organic compound characterized by its multi-cyclic structure, which includes a benzo[b]thiophene core and various functional groups such as a carbonitrile, amino, and trifluoromethyl groups. This compound exhibits significant molecular diversity due to the presence of multiple stereocenters and substituents, which can influence its biological activity and chemical reactivity. The presence of fluorine atoms typically enhances lipophilicity and metabolic stability, making such compounds of interest in medicinal chemistry. Additionally, the piperazine and pyrrolidine moieties may contribute to its pharmacological properties, potentially impacting receptor binding and activity. Overall, this compound's intricate structure suggests potential applications in drug development, particularly in targeting specific biological pathways.

Formula: C₃₅H₃₃F₆N₇O₂S

Synonyms:

• Benzo[b]thiophene-3-carbonitrile, 2-amino-4-[4-[(2S,5R)-2,5-dimethyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]-6-(trifluoromethyl)-7-quinazolinyl]-7-fluoro-, (4S)-

BBO-8520

CAS: 2893809-51-1

BBO-8520 is a dual KRASG12C inhibitor that blocks ON and OFF states, disables effector binding, suppresses signaling, and induces tumor regression.

Formula: C₃₅H₃₃F₆N₇O₂S

Purity: 97.879%

Color and Shape: Solid

Molecular weight: 729.74

Ref: TM-T85809