CAS: 289499-45-2 - Canertinib dihydrochloride

Formula: C₂₄H₂₅ClFN₅O₃

InChI: InChI=1S/C24H25ClFN5O3.2ClH/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16;;/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29);2*1H

InChI key: InChIKey=JZZFDCXSFTVOJY-UHFFFAOYSA-N

SMILES: Cl.O=C(C=C)NC1=CC=2C(=NC=NC2NC3=CC=C(F)C(Cl)=C3)C=C1OCCCN4CCOCC4

Synonyms:

• 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-, dihydrochloride
• 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-, hydrochloride (1:2)
• Canertinib 2HCl
• Ci 1033
• N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide dihydrochloride
• N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[2-(morpholin-4-yl)ethoxy]quinazolin-6-yl}prop-2-enamide dihydrochloride
• N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide dihydrochloride
• Pd 183805

2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-, hydrochloride (1:2)

CAS: 289499-45-2

• Formula: C₂₄H₂₇Cl₃FN₅O₃
• Purity: 98% (HPLC)
• Color and Shape: Solid
• Molecular weight: 558.8603

Canertinib dihydrochloride

CAS: 289499-45-2

• Formula: C₂₄H₂₅ClFN₅O₃₂HCl
• Molecular weight: 558.86

Canertinib dihydrochloride

CAS: 289499-45-2

Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential …

• Formula: C₂₄H₂₇Cl₃FN₅O₃
• Purity: 99.23%
• Color and Shape: Solid
• Molecular weight: 558.86

Canertinib dihydrochloride

CAS: 289499-45-2

Inhibitor of EGFR, HER2 and HER4 tyrosine kinases

• Formula: C₂₄H₂₅ClFN₅O₃·2HCl
• Purity: Min. 95%
• Molecular weight: 558.86